A Multimodal Fitting Approach to Construct Single-Neuron Models With Patch Clamp and High-Density Microelectrode Arrays

In computational neuroscience, multicompartment models are among the most biophysically realistic representations of single neurons. Constructing such models usually involves the use of the patch-clamp technique to record somatic voltage signals under different experimental conditions. The experimen...

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Veröffentlicht in:	Neural computation 2024-06, Vol.36 (7), p.1286-1331
Hauptverfasser:	Buccino, Alessio Paolo, Damart, Tanguy, Bartram, Julian, Mandge, Darshan, Xue, Xiaohan, Zbili, Mickael, Gänswein, Tobias, Jaquier, Aurélien, Emmenegger, Vishalini, Markram, Henry, Hierlemann, Andreas, Van Geit, Werner
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - physiology Animals Computer Science Computer Simulation Life Sciences Microelectrodes Modeling and Simulation Models, Neurological Neurobiology Neurons - physiology Neurons and Cognition Patch-Clamp Techniques - instrumentation Patch-Clamp Techniques - methods
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