Cytidine Deaminase Deficiency Reveals New Therapeutic Opportunities against Cancer

Abstract Purpose: One of the main challenges in cancer therapy is the identification of molecular mechanisms mediating resistance or sensitivity to treatment. Cytidine deaminase (CDA) was reported to be downregulated in cells derived from patients with Bloom syndrome, a genetic disease associated wi...

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Veröffentlicht in:	Clinical cancer research 2017-04, Vol.23 (8), p.2116-2126
Hauptverfasser:	Mameri, Hamza, Bièche, Ivan, Meseure, Didier, Marangoni, Elisabetta, Buhagiar-Labarchède, Géraldine, Nicolas, André, Vacher, Sophie, Onclercq-Delic, Rosine, Rajapakse, Vinodh, Varma, Sudhir, Reinhold, William, Pommier, Yves, Amor-Guéret, Mounira
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry, Molecular Biology Cancer Cellular Biology Genomics Life Sciences
Online-Zugang:	Volltext
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