Towards a General Access to 1‐Azaspirocyclic Systems via Photoinduced, Reductive Decarboxylative Radical Cyclizations

A convenient and versatile approach to important 1‐azaspirocyclic systems relevant to medicinal chemistry and natural products is reported herein. The main strategy relies on a reductive decarboxylative cyclization of redox‐active esters which can be rapidly assembled from abundant cyclic azaacids a...

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Veröffentlicht in:	Chemistry : a European journal 2024-03, Vol.30 (13), p.e202303841-n/a
Hauptverfasser:	Kiprova, Natalia, Desnoyers, Marine, Narobe, Rok, Klufts‐Edel, Arthur, Chaud, Juliane, König, Burkhard, Compain, Philippe, Kern, Nicolas
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkynes azaspirocycles Chemical Sciences decarboxylation Esters Natural products Organic chemistry Organometallic compounds photoredox radicals Substrates
Online-Zugang:	Volltext
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