Baseline metabolic tumor burden on FDG PET/CT scans predicts outcome in advanced NSCLC patients treated with immune checkpoint inhibitors

Purpose We aimed to evaluate if imaging biomarkers on FDG PET are associated with clinical outcomes in patients with advanced non-small cell lung cancer (NSCLC) treated with immune checkpoint inhibitors (ICIs). Methods In this retrospective monocentric study, we included 109 patients with advanced N...

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Veröffentlicht in:	European journal of nuclear medicine and molecular imaging 2020-05, Vol.47 (5), p.1147-1157
Hauptverfasser:	Seban, Romain-David, Mezquita, Laura, Berenbaum, Arnaud, Dercle, Laurent, Botticella, Angela, Le Pechoux, Cécile, Caramella, Caroline, Deutsch, Eric, Grimaldi, Serena, Adam, Julien, Ammari, Samy, Planchard, David, Leboulleux, Sophie, Besse, Benjamin
Format:	Artikel
Sprache:	eng
Schlagworte:	Anemia Biomarkers Carcinoma, Non-Small-Cell Lung - diagnostic imaging Carcinoma, Non-Small-Cell Lung - drug therapy Cardiology Computed tomography Fluorodeoxyglucose F18 Humans Imaging Immune Checkpoint Inhibitors Inflammation Inhibitors Leukocytes Leukocytes (neutrophilic) Life Sciences Lung cancer Lung Neoplasms - diagnostic imaging Lung Neoplasms - drug therapy Medical imaging Medicine Medicine & Public Health Metabolism Multivariate analysis Neutrophils Non-small cell lung carcinoma Nuclear Medicine Oncology Oncology – Chest Original Article Orthopedics Patients Positron emission Positron emission tomography Positron Emission Tomography Computed Tomography Prediction models Prognosis Radiology Regression analysis Retrospective Studies Small cell lung carcinoma Survival Tomography Tumor Burden Tumors
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