Phase I Trial of Debio 1143, an Antagonist of Inhibitor of Apoptosis Proteins, Combined with Cisplatin Chemoradiotherapy in Patients with Locally Advanced Squamous Cell Carcinoma of the Head and Neck

Debio 1143 is an oral antagonist of inhibitor of apoptosis proteins, which enhances tumor response with concomitant chemoradiotherapy. Addition of Debio 1143 to cisplatin-based chemoradiotherapy in locally advanced squamous cell carcinomas of the head and neck (LA-SCCHN) was evaluated in a phase I/I...

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Veröffentlicht in:	Clinical cancer research 2020-12, Vol.26 (24), p.6429-6436
Hauptverfasser:	Le Tourneau, Christophe, Tao, Yungan, Gomez-Roca, Carlos, Cristina, Valerie, Borcoman, Edith, Deutsch, Eric, Bahleda, Rastislav, Calugaru, Valentin, Modesto, Anouchka, Rouits, Elisabeth, Gollmer, Kathrin, Vuagniaux, Gregoire, Crompton, Philippa, Zanna, Claudio, Szyldergemajn, Sergio, Delord, Jean-Pierre, Bourhis, Jean
Format:	Artikel
Sprache:	eng
Schlagworte:	Life Sciences
Online-Zugang:	Volltext
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