TERT Promoter Mutations Increase Sense and Antisense Transcription from the TERT Promoter

Background: Chief among mechanisms of telomerase reverse transcriptase (TERT) reactivation is the appearance of mutations in the TERT promoter. The two main TERT promoter mutations are C>T transitions located −146C>T and −124C>T upstream from the translational start site. They generate a no...

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Veröffentlicht in:	Biomedicines 2021-11, Vol.9 (12)
Hauptverfasser:	Hafezi, François, Jaxel, Lisa, Lemaire, Morgane, Turner, Jonathan, Perez-Bercoff, Danielle
Format:	Artikel
Sprache:	eng
Schlagworte:	Life Sciences
Online-Zugang:	Volltext
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