Assessing the role of phosphorylated S6 ribosomal protein in the pathological diagnosis of pulmonary antibody-mediated rejection

Pulmonary antibody-mediated rejection is still a challenging diagnosis as C4d immunostaining has poor sensitivity. Previous studies have indicated that the phosphorylated S6 ribosomal protein, a component of the mammalian target of rapamycin (mTOR) pathway, is correlated with de novo donor-specific...

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Veröffentlicht in:	The Journal of heart and lung transplantation 2024-03, Vol.43 (3), p.403-413
Hauptverfasser:	Lunardi, Francesca, Vedovelli, Luca, Pezzuto, Federica, Le Pavec, Jerome, Dorfmuller, Peter, Ivanovic, Marina, Pena, Tahuanty, Wassilew, Katharina, Perch, Michael, Hirschi, Sandrine, Chenard, Marie-Pierre, Sosa, Rebecca A., Goddard, Martin, Neil, Desley, Montero-Fernandez, Angeles, Rice, Alexandra, Cozzi, Emanuele, Rea, Federico, Levine, Deborah J., Roux, Antoine, Fishbein, Gregory A., Calabrese, Fiorella
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies antibody-mediated rejection antibody-mediated rejection (AMR) Humanities and Social Sciences Humans Life Sciences Lung - metabolism lung transplantation mammalian target of rapamycin (mTOR) pathway phosphorylated s6 ribosomal protein (p-S6RP) Retrospective Studies Ribosomal Proteins Sirolimus TOR Serine-Threonine Kinases - metabolism
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