The unlikely partnership between LRRK 2 and α‐synuclein in Parkinson's disease

Our understanding of the mechanisms underlying Parkinson's disease, the once archetypical nongenetic neurogenerative disorder, has dramatically increased with the identification of α‐synuclein and LRRK 2 pathogenic mutations. While α‐synuclein protein composes the aggregates that can spread thr...

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Veröffentlicht in:The European journal of neuroscience 2019-02, Vol.49 (3), p.339-363
Hauptverfasser: Cresto, Noémie, Gardier, Camille, Gubinelli, Francesco, Gaillard, Marie‐Claude, Liot, Géraldine, West, Andrew B., Brouillet, Emmanuel
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Sprache:eng
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