Involvement of CCL18 in Allergic Asthma

Allergic asthma is associated with a pulmonary recruitment of Th type 2 cells, basophils, and eosinophils, mainly linked to chemokine production. CCL18 is a chemokine preferentially expressed in the lung, secreted by APCs, induced by Th2-type cytokines, and only present in humans. Therefore, CCL18 m...

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Veröffentlicht in:	Journal of Immunology 2006-05, Vol.176 (10), p.6286-6293
Hauptverfasser:	Nadai, Patricia de, Charbonnier, Anne-Sophie, Chenivesse, Cecile, Senechal, Stephanie, Fournier, Clement, Gilet, Jules, Vorng, Han, Chang, Ying, Gosset, Philippe, Wallaert, Benoit, Tonnel, Andre-Bernard, Lassalle, Philippe, Tsicopoulos, Anne
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergens - immunology Animals Antigens, Dermatophagoides - immunology Arthropod Proteins Asthma - immunology Asthma - metabolism Basophils - metabolism Cells, Cultured Chemokines, CC - genetics Chemokines, CC - metabolism Chemokines, CC - physiology Cysteine Endopeptidases Dermatophagoides pteronyssinus Humans Life Sciences Lymphocyte Activation - immunology Mice Mice, Inbred C57BL Pyroglyphidae - immunology RNA, Messenger - biosynthesis RNA, Messenger - metabolism Th2 Cells - metabolism Up-Regulation - immunology
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