Identification of Carotid Plaques Composition Through a Compact CSRR-Based Microwave Sensor
This study aims to identify the dielectric constant of the carotid atherosclerotic plaques and categorise them using a CSRR based microwave sensor. A Complementary Split Ring Resonator (CSRR) at 2.3 GHz measured 33 samples of carotid plaques obtained after endarterectomy. HFSS software simulations w...
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Veröffentlicht in: | Ingénierie et recherche biomédicale 2023-04, Vol.44 (2), p.100734, Article 100734 |
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creator | Shahbaz, R. Deshours, F. Alquie, G. Kokabi, H. Koskas, F. Brocheriou, I. Le Naour, G. Hannachi, C. Davaine, J.-M. |
description | This study aims to identify the dielectric constant of the carotid atherosclerotic plaques and categorise them using a CSRR based microwave sensor.
A Complementary Split Ring Resonator (CSRR) at 2.3 GHz measured 33 samples of carotid plaques obtained after endarterectomy. HFSS software simulations were employed to substantiate the measurements. Histological analyses were performed simultaneously to classify the plaques.
The constant dielectric of dangerous carotid plaques identified by histology was much higher than that of low-risk calcified carotid plaques. Microwave data were pertinent to the simulations.
The current study, performed on ex-vivo carotid plaques, illustrates the sensor's ability to differentiate plaques with diverse components. Calcified low-risk plaques displayed distinct values from dangerous soft plaques. Further statistical correlation of the 33 samples is required. After validation, an in-vivo prototype will be designed and tested.
•Carotid plaques are identified via the dielectric constant using a microwave sensor.•The sensor differentiated calcified carotid plaques from plaques at risk.•A pre-op modality that can identify the composition of the carotid plaque in vivo.•Correlation of the histological analysis with the dielectric parameters. |
doi_str_mv | 10.1016/j.irbm.2022.09.001 |
format | Article |
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A Complementary Split Ring Resonator (CSRR) at 2.3 GHz measured 33 samples of carotid plaques obtained after endarterectomy. HFSS software simulations were employed to substantiate the measurements. Histological analyses were performed simultaneously to classify the plaques.
The constant dielectric of dangerous carotid plaques identified by histology was much higher than that of low-risk calcified carotid plaques. Microwave data were pertinent to the simulations.
The current study, performed on ex-vivo carotid plaques, illustrates the sensor's ability to differentiate plaques with diverse components. Calcified low-risk plaques displayed distinct values from dangerous soft plaques. Further statistical correlation of the 33 samples is required. After validation, an in-vivo prototype will be designed and tested.
•Carotid plaques are identified via the dielectric constant using a microwave sensor.•The sensor differentiated calcified carotid plaques from plaques at risk.•A pre-op modality that can identify the composition of the carotid plaque in vivo.•Correlation of the histological analysis with the dielectric parameters.</description><identifier>ISSN: 1959-0318</identifier><identifier>DOI: 10.1016/j.irbm.2022.09.001</identifier><language>eng</language><publisher>Elsevier Masson SAS</publisher><subject>Biosensor ; Carotid plaque ; CSRR ; Engineering Sciences ; Microwave ; Resonator</subject><ispartof>Ingénierie et recherche biomédicale, 2023-04, Vol.44 (2), p.100734, Article 100734</ispartof><rights>2022 AGBM</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c329t-c063d315491745e7d0d11f8fc234c14d4982f6e3308f5ba3af154b1477babd943</cites><orcidid>0000-0003-3857-7123 ; 0000-0003-2094-4888 ; 0000-0003-0134-5783 ; 0000-0002-0092-3898 ; 0000-0001-7867-6711</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.irbm.2022.09.001$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,315,781,785,886,3551,27929,27930,46000</link.rule.ids><backlink>$$Uhttps://hal.science/hal-04460749$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Shahbaz, R.</creatorcontrib><creatorcontrib>Deshours, F.</creatorcontrib><creatorcontrib>Alquie, G.</creatorcontrib><creatorcontrib>Kokabi, H.</creatorcontrib><creatorcontrib>Koskas, F.</creatorcontrib><creatorcontrib>Brocheriou, I.</creatorcontrib><creatorcontrib>Le Naour, G.</creatorcontrib><creatorcontrib>Hannachi, C.</creatorcontrib><creatorcontrib>Davaine, J.-M.</creatorcontrib><title>Identification of Carotid Plaques Composition Through a Compact CSRR-Based Microwave Sensor</title><title>Ingénierie et recherche biomédicale</title><description>This study aims to identify the dielectric constant of the carotid atherosclerotic plaques and categorise them using a CSRR based microwave sensor.
A Complementary Split Ring Resonator (CSRR) at 2.3 GHz measured 33 samples of carotid plaques obtained after endarterectomy. HFSS software simulations were employed to substantiate the measurements. Histological analyses were performed simultaneously to classify the plaques.
The constant dielectric of dangerous carotid plaques identified by histology was much higher than that of low-risk calcified carotid plaques. Microwave data were pertinent to the simulations.
The current study, performed on ex-vivo carotid plaques, illustrates the sensor's ability to differentiate plaques with diverse components. Calcified low-risk plaques displayed distinct values from dangerous soft plaques. Further statistical correlation of the 33 samples is required. After validation, an in-vivo prototype will be designed and tested.
•Carotid plaques are identified via the dielectric constant using a microwave sensor.•The sensor differentiated calcified carotid plaques from plaques at risk.•A pre-op modality that can identify the composition of the carotid plaque in vivo.•Correlation of the histological analysis with the dielectric parameters.</description><subject>Biosensor</subject><subject>Carotid plaque</subject><subject>CSRR</subject><subject>Engineering Sciences</subject><subject>Microwave</subject><subject>Resonator</subject><issn>1959-0318</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNp9kEtPAjEUhbvQRET_gKtuXczY1zyauMGJAglGA7hy0XT6kBKYYjtg_PfOgHHp6ibnnu_m3APADUYpRji_W6cu1NuUIEJSxFOE8BkYYJ7xBFFcXoDLGNcI5ZRQPADvU22a1lmnZOt8A72FlQy-dRq-buTn3kRY-e3OR3dcL1fB7z9WUB5VqVpYLebz5EFGo-GzU8F_yYOBC9NEH67AuZWbaK5_5xC8PT0uq0kyexlPq9EsUZTwNlFdFk1xxjguWGYKjTTGtrSKUKYw04yXxOaGUlTarJZU2s5bY1YUtaw1Z3QIbk93V3IjdsFtZfgWXjoxGc1EryHGclQwfsCdl5y8XdQYg7F_AEair0-sRV-f6OsTiIuuvg66P0Gm--LgTBBROdMoo10wqhXau__wH6KHej0</recordid><startdate>20230401</startdate><enddate>20230401</enddate><creator>Shahbaz, R.</creator><creator>Deshours, F.</creator><creator>Alquie, G.</creator><creator>Kokabi, H.</creator><creator>Koskas, F.</creator><creator>Brocheriou, I.</creator><creator>Le Naour, G.</creator><creator>Hannachi, C.</creator><creator>Davaine, J.-M.</creator><general>Elsevier Masson SAS</general><general>Elsevier Masson</general><scope>AAYXX</scope><scope>CITATION</scope><scope>1XC</scope><orcidid>https://orcid.org/0000-0003-3857-7123</orcidid><orcidid>https://orcid.org/0000-0003-2094-4888</orcidid><orcidid>https://orcid.org/0000-0003-0134-5783</orcidid><orcidid>https://orcid.org/0000-0002-0092-3898</orcidid><orcidid>https://orcid.org/0000-0001-7867-6711</orcidid></search><sort><creationdate>20230401</creationdate><title>Identification of Carotid Plaques Composition Through a Compact CSRR-Based Microwave Sensor</title><author>Shahbaz, R. ; Deshours, F. ; Alquie, G. ; Kokabi, H. ; Koskas, F. ; Brocheriou, I. ; Le Naour, G. ; Hannachi, C. ; Davaine, J.-M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c329t-c063d315491745e7d0d11f8fc234c14d4982f6e3308f5ba3af154b1477babd943</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Biosensor</topic><topic>Carotid plaque</topic><topic>CSRR</topic><topic>Engineering Sciences</topic><topic>Microwave</topic><topic>Resonator</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shahbaz, R.</creatorcontrib><creatorcontrib>Deshours, F.</creatorcontrib><creatorcontrib>Alquie, G.</creatorcontrib><creatorcontrib>Kokabi, H.</creatorcontrib><creatorcontrib>Koskas, F.</creatorcontrib><creatorcontrib>Brocheriou, I.</creatorcontrib><creatorcontrib>Le Naour, G.</creatorcontrib><creatorcontrib>Hannachi, C.</creatorcontrib><creatorcontrib>Davaine, J.-M.</creatorcontrib><collection>CrossRef</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>Ingénierie et recherche biomédicale</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shahbaz, R.</au><au>Deshours, F.</au><au>Alquie, G.</au><au>Kokabi, H.</au><au>Koskas, F.</au><au>Brocheriou, I.</au><au>Le Naour, G.</au><au>Hannachi, C.</au><au>Davaine, J.-M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Identification of Carotid Plaques Composition Through a Compact CSRR-Based Microwave Sensor</atitle><jtitle>Ingénierie et recherche biomédicale</jtitle><date>2023-04-01</date><risdate>2023</risdate><volume>44</volume><issue>2</issue><spage>100734</spage><pages>100734-</pages><artnum>100734</artnum><issn>1959-0318</issn><abstract>This study aims to identify the dielectric constant of the carotid atherosclerotic plaques and categorise them using a CSRR based microwave sensor.
A Complementary Split Ring Resonator (CSRR) at 2.3 GHz measured 33 samples of carotid plaques obtained after endarterectomy. HFSS software simulations were employed to substantiate the measurements. Histological analyses were performed simultaneously to classify the plaques.
The constant dielectric of dangerous carotid plaques identified by histology was much higher than that of low-risk calcified carotid plaques. Microwave data were pertinent to the simulations.
The current study, performed on ex-vivo carotid plaques, illustrates the sensor's ability to differentiate plaques with diverse components. Calcified low-risk plaques displayed distinct values from dangerous soft plaques. Further statistical correlation of the 33 samples is required. After validation, an in-vivo prototype will be designed and tested.
•Carotid plaques are identified via the dielectric constant using a microwave sensor.•The sensor differentiated calcified carotid plaques from plaques at risk.•A pre-op modality that can identify the composition of the carotid plaque in vivo.•Correlation of the histological analysis with the dielectric parameters.</abstract><pub>Elsevier Masson SAS</pub><doi>10.1016/j.irbm.2022.09.001</doi><orcidid>https://orcid.org/0000-0003-3857-7123</orcidid><orcidid>https://orcid.org/0000-0003-2094-4888</orcidid><orcidid>https://orcid.org/0000-0003-0134-5783</orcidid><orcidid>https://orcid.org/0000-0002-0092-3898</orcidid><orcidid>https://orcid.org/0000-0001-7867-6711</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Biosensor Carotid plaque CSRR Engineering Sciences Microwave Resonator |
title | Identification of Carotid Plaques Composition Through a Compact CSRR-Based Microwave Sensor |
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