Endothelial cell surface limits coagulation without modulating the antithrombin potency

Antithrombin (AT) binds in vitro and in vivo to endothelial cells through various receptors, including heparan sulphate glycosaminoglycan (HSPG) that could modulate the AT activity. A thrombin generation assay (TGA) was set up at the surface of HUVEC and HMVEC evaluating their participation in the c...

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Veröffentlicht in:	Thrombosis research 2018-07, Vol.167, p.88-95
Hauptverfasser:	Catieau, Béatrice, Devos, Véronique, Chtourou, Sami, Borgel, Delphine, Plantier, Jean-Luc
Format:	Artikel
Sprache:	eng
Schlagworte:	Antithrombin Endothelial cells Hematology Heparan sulphates Human health and pathology Life Sciences Thrombin generation assay
Online-Zugang:	Volltext
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