Antithrombotic potential of a single‐domain antibody enhancing the activated protein C‐cofactor activity of protein S

Background Protein S (PS) is a natural anticoagulant acting as a cofactor for activated protein C (APC) in the proteolytic inactivation of activated factors V (FVa) and VIII (FVIIIa), but also for tissue factor pathway inhibitor α (TFPIα) in the inhibition of activated factor X (FXa). Objective For...

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Veröffentlicht in:Journal of thrombosis and haemostasis 2022-07, Vol.20 (7), p.1653-1664
Hauptverfasser: Sedzro, Josepha C., Adam, Frédéric, Auditeau, Claire, Bianchini, Elsa, De Carvalho, Allan, Peyron, Ivan, Daramé, Sadyo, Gandrille, Sophie, Thomassen, Stella, Hackeng, Tilman M., Christophe, Olivier D., Lenting, Peter J., Denis, Cécile V., Borgel, Delphine, Saller, François
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Sprache:eng
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