Synthesis of Original Cyclic Dinucleotide Analogues Using the Sulfo-click Reaction

The stimulator of interferon genes (STING) protein plays a crucial role in the activation of the innate immune response. Activation of STING is initiated by cyclic dinucleotides (CDNs) which prompted the community to synthesize structural analogues to enhance their biological properties. We present...

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Veröffentlicht in:	Organic letters 2024-02, Vol.26 (4), p.819-823
Hauptverfasser:	Amador, Romain, Vasseur, Jean-Jacques, Birkuš, Gabriel, Bignon, Emmanuelle, Monari, Antonio, Clavé, Guillaume, Smietana, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemical Sciences Nucleotides, Cyclic - chemistry Nucleotides, Cyclic - metabolism
Online-Zugang:	Volltext
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