Merging Iridium-Catalyzed Stereoselective Coupling from Alcohols with Organocatalytic Functionalization at the Aldehyde Oxidation Level

We report the selective merging between a Krische-type iridium-catalyzed C–C coupling and an organocatalyzed oxa-Michael addition. Such a general strategy triggers the direct double functionalization of alcohols through a complex multicatalytic pathway, merging the two catalytic cycles in one. The i...

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Veröffentlicht in:ACS catalysis 2023-11, Vol.13 (22), p.14945-14952
Hauptverfasser: Alexandridis, Anestis, Quintard, Adrien
Format: Artikel
Sprache:eng
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