Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis thaliana

The plant Arabidopsis thaliana (Arabidopsis) has become an important model species for the study of many aspects of plant biology 1 . The relatively small size of the nuclear genome and the availability of extensive physical maps of the five chromosomes 2 , 3 , 4 provide a feasible basis for initiat...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature (London) 1998-01, Vol.391 (6666), p.485-488
Hauptverfasser:	The EU Arabidopsis Genome Project, Bevan, M., Bancroft, I., Bent, E., Love, K., Goodman, H., Dean, C., Bergkamp, R., Dirkse, W., Van Staveren, M., Stiekema, W., Drost, L., Ridley, P., Hudson, S.-A., Patel, K., Murphy, G., Piffanelli, P., Wedler, H., Wedler, E., Wambutt, R., Weitzenegger, T., Pohl, T. M., Terryn, N., Gielen, J., Villarroel, R., De Clerck, R., Van Montagu, M., Lecharny, A., Auborg, S., Gy, I., Kreis, M., Lao, N., Kavanagh, T., Hempel, S., Kotter, P., Entian, K.-D., Rieger, M., Schaeffer, M., Funk, B., Mueller-Auer, S., Silvey, M., James, R., Montfort, A., Pons, A., Puigdomenech, P., Douka, A., Voukelatou, E., Milioni, D., Hatzopoulos, P., Piravandi, E., Obermaier, B., Hilbert, H., Düsterhöft, A., Moores, T., Jones, J. D. G., Eneva, T., Palme, K., Benes, V., Rechman, S., Ansorge, W., Cooke, R., Berger, C., Delseny, M., Voet, M., Volckaert, G., Mewes, H.-W., Klosterman, S., Schueller, C., Chalwatzis, N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Arabidopsis - genetics Biological and medical sciences Chromosome Mapping Chromosomes Chromosomes, Artificial, Yeast Classical genetics, quantitative genetics, hybrids Fundamental and applied biological sciences. Psychology Genes Genes, Plant - physiology Genetics Genetics of eukaryotes. Biological and molecular evolution Genome, Plant Humanities and Social Sciences letter Life Sciences multidisciplinary Multigene Family Plant Proteins - genetics Pteridophyta, spermatophyta Science Science (multidisciplinary) Sequence Analysis, DNA Vegetals Weeds Yeasts
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

container_end_page	488
container_issue	6666
container_start_page	485
container_title	Nature (London)
container_volume	391
creator	The EU Arabidopsis Genome Project Bevan, M. Bancroft, I. Bent, E. Love, K. Goodman, H. Dean, C. Bergkamp, R. Dirkse, W. Van Staveren, M. Stiekema, W. Drost, L. Ridley, P. Hudson, S.-A. Patel, K. Murphy, G. Piffanelli, P. Wedler, H. Wedler, E. Wambutt, R. Weitzenegger, T. Pohl, T. M. Terryn, N. Gielen, J. Villarroel, R. De Clerck, R. Van Montagu, M. Lecharny, A. Auborg, S. Gy, I. Kreis, M. Lao, N. Kavanagh, T. Hempel, S. Kotter, P. Entian, K.-D. Rieger, M. Schaeffer, M. Funk, B. Mueller-Auer, S. Silvey, M. James, R. Montfort, A. Pons, A. Puigdomenech, P. Douka, A. Voukelatou, E. Milioni, D. Hatzopoulos, P. Piravandi, E. Obermaier, B. Hilbert, H. Düsterhöft, A. Moores, T. Jones, J. D. G. Eneva, T. Palme, K. Benes, V. Rechman, S. Ansorge, W. Cooke, R. Berger, C. Delseny, M. Voet, M. Volckaert, G. Mewes, H.-W. Klosterman, S. Schueller, C. Chalwatzis, N.
description	The plant Arabidopsis thaliana (Arabidopsis) has become an important model species for the study of many aspects of plant biology 1 . The relatively small size of the nuclear genome and the availability of extensive physical maps of the five chromosomes 2 , 3 , 4 provide a feasible basis for initiating sequencing of the five chromosomes. The YAC (yeast artificial chromosome)-based physical map of chromosome 4 was used to construct a sequence-ready map of cosmid and BAC (bacterial artificial chromosome) clones covering a 1.9-megabase (Mb) contiguous region 5 , and the sequence of this region is reported here. Analysis of the sequence revealed an average gene density of one gene every 4.8 kilobases (kb), and 54% of the predicted genes had significant similarity to known genes. Other interesting features were found, such as the sequence of a disease-resistance gene locus, the distribution of retroelements, the frequent occurrence of clustered gene families, and the sequence of several classes of genes not previously encountered in plants.
doi_str_mv	10.1038/35140
format	Article
fullrecord	<record><control><sourceid>proquest_hal_p</sourceid><recordid>TN_cdi_hal_primary_oai_HAL_hal_04402918v1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>743709884</sourcerecordid><originalsourceid>FETCH-LOGICAL-c522t-bd6211baba4c7e5a7c09f95474cbeab5e12d01fca0bca5d03d51d1b3f2b547723</originalsourceid><addsrcrecordid>eNqFkc1u1DAUhS0EKkPpIyBFiB-xSLnX_1mOKqBIg9jQtWU7TpsqiQd7gtQdW16TJ8FhRlPBAja25fvp3HvuIeQM4RyB6bdMIIcHZIVcyZpLrR6SFQDVNWgmH5MnOd8CgEDFT8hJwyVSFCtytZ7scJf7XMWuwvPm5_cfn9zy9nHa9ddznHOVw9c5TD5UXYpj5W_KGXMcQ8UXcJ2s69u4XTR2N3bo7WSfkkedHXI4O9yn5Or9uy8Xl_Xm84ePF-tN7QWlu9q1kiI66yz3KgirPDRdI7ji3gXrREDaAnbegvNWtMBagS061lFXIEXZKXmz1y19zTb1o013JtreXK43ZvkDzoE2qL9hYV_t2W2KxU_embHPPgyDnUJxaVQjtUBYwNf_BjlT0GjN_yuJkkrGtSzg87_A2zinsvlsaBlRihJHgV7uIZ9izil0R0cIZonY_I64cM8OYrMbQ3ukDpmW-otD3WZvhy7Zyff5iJWNM1TifvhcKtN1SPcz_dnvF9mMt0A</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>204465461</pqid></control><display><type>article</type><title>Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis thaliana</title><source>MEDLINE</source><source>Springer Online Journals</source><source>Springer Nature - Connect here FIRST to enable access</source><creator>The EU Arabidopsis Genome Project ; Bevan, M. ; Bancroft, I. ; Bent, E. ; Love, K. ; Goodman, H. ; Dean, C. ; Bergkamp, R. ; Dirkse, W. ; Van Staveren, M. ; Stiekema, W. ; Drost, L. ; Ridley, P. ; Hudson, S.-A. ; Patel, K. ; Murphy, G. ; Piffanelli, P. ; Wedler, H. ; Wedler, E. ; Wambutt, R. ; Weitzenegger, T. ; Pohl, T. M. ; Terryn, N. ; Gielen, J. ; Villarroel, R. ; De Clerck, R. ; Van Montagu, M. ; Lecharny, A. ; Auborg, S. ; Gy, I. ; Kreis, M. ; Lao, N. ; Kavanagh, T. ; Hempel, S. ; Kotter, P. ; Entian, K.-D. ; Rieger, M. ; Schaeffer, M. ; Funk, B. ; Mueller-Auer, S. ; Silvey, M. ; James, R. ; Montfort, A. ; Pons, A. ; Puigdomenech, P. ; Douka, A. ; Voukelatou, E. ; Milioni, D. ; Hatzopoulos, P. ; Piravandi, E. ; Obermaier, B. ; Hilbert, H. ; Düsterhöft, A. ; Moores, T. ; Jones, J. D. G. ; Eneva, T. ; Palme, K. ; Benes, V. ; Rechman, S. ; Ansorge, W. ; Cooke, R. ; Berger, C. ; Delseny, M. ; Voet, M. ; Volckaert, G. ; Mewes, H.-W. ; Klosterman, S. ; Schueller, C. ; Chalwatzis, N.</creator><creatorcontrib>The EU Arabidopsis Genome Project ; Bevan, M. ; Bancroft, I. ; Bent, E. ; Love, K. ; Goodman, H. ; Dean, C. ; Bergkamp, R. ; Dirkse, W. ; Van Staveren, M. ; Stiekema, W. ; Drost, L. ; Ridley, P. ; Hudson, S.-A. ; Patel, K. ; Murphy, G. ; Piffanelli, P. ; Wedler, H. ; Wedler, E. ; Wambutt, R. ; Weitzenegger, T. ; Pohl, T. M. ; Terryn, N. ; Gielen, J. ; Villarroel, R. ; De Clerck, R. ; Van Montagu, M. ; Lecharny, A. ; Auborg, S. ; Gy, I. ; Kreis, M. ; Lao, N. ; Kavanagh, T. ; Hempel, S. ; Kotter, P. ; Entian, K.-D. ; Rieger, M. ; Schaeffer, M. ; Funk, B. ; Mueller-Auer, S. ; Silvey, M. ; James, R. ; Montfort, A. ; Pons, A. ; Puigdomenech, P. ; Douka, A. ; Voukelatou, E. ; Milioni, D. ; Hatzopoulos, P. ; Piravandi, E. ; Obermaier, B. ; Hilbert, H. ; Düsterhöft, A. ; Moores, T. ; Jones, J. D. G. ; Eneva, T. ; Palme, K. ; Benes, V. ; Rechman, S. ; Ansorge, W. ; Cooke, R. ; Berger, C. ; Delseny, M. ; Voet, M. ; Volckaert, G. ; Mewes, H.-W. ; Klosterman, S. ; Schueller, C. ; Chalwatzis, N.</creatorcontrib><description>The plant Arabidopsis thaliana (Arabidopsis) has become an important model species for the study of many aspects of plant biology 1 . The relatively small size of the nuclear genome and the availability of extensive physical maps of the five chromosomes 2 , 3 , 4 provide a feasible basis for initiating sequencing of the five chromosomes. The YAC (yeast artificial chromosome)-based physical map of chromosome 4 was used to construct a sequence-ready map of cosmid and BAC (bacterial artificial chromosome) clones covering a 1.9-megabase (Mb) contiguous region 5 , and the sequence of this region is reported here. Analysis of the sequence revealed an average gene density of one gene every 4.8 kilobases (kb), and 54% of the predicted genes had significant similarity to known genes. Other interesting features were found, such as the sequence of a disease-resistance gene locus, the distribution of retroelements, the frequent occurrence of clustered gene families, and the sequence of several classes of genes not previously encountered in plants.</description><identifier>ISSN: 0028-0836</identifier><identifier>EISSN: 1476-4687</identifier><identifier>DOI: 10.1038/35140</identifier><identifier>PMID: 9461215</identifier><identifier>CODEN: NATUAS</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Arabidopsis - genetics ; Biological and medical sciences ; Chromosome Mapping ; Chromosomes ; Chromosomes, Artificial, Yeast ; Classical genetics, quantitative genetics, hybrids ; Fundamental and applied biological sciences. Psychology ; Genes ; Genes, Plant - physiology ; Genetics ; Genetics of eukaryotes. Biological and molecular evolution ; Genome, Plant ; Humanities and Social Sciences ; letter ; Life Sciences ; multidisciplinary ; Multigene Family ; Plant Proteins - genetics ; Pteridophyta, spermatophyta ; Science ; Science (multidisciplinary) ; Sequence Analysis, DNA ; Vegetals ; Weeds ; Yeasts</subject><ispartof>Nature (London), 1998-01, Vol.391 (6666), p.485-488</ispartof><rights>Macmillan Magazines Ltd. 1998</rights><rights>1998 INIST-CNRS</rights><rights>Copyright Macmillan Journals Ltd. Jan 29, 1998</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c522t-bd6211baba4c7e5a7c09f95474cbeab5e12d01fca0bca5d03d51d1b3f2b547723</citedby><cites>FETCH-LOGICAL-c522t-bd6211baba4c7e5a7c09f95474cbeab5e12d01fca0bca5d03d51d1b3f2b547723</cites><orcidid>0000-0002-0695-4767</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/35140$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/35140$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,776,780,881,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2113175$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9461215$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-04402918$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>The EU Arabidopsis Genome Project</creatorcontrib><creatorcontrib>Bevan, M.</creatorcontrib><creatorcontrib>Bancroft, I.</creatorcontrib><creatorcontrib>Bent, E.</creatorcontrib><creatorcontrib>Love, K.</creatorcontrib><creatorcontrib>Goodman, H.</creatorcontrib><creatorcontrib>Dean, C.</creatorcontrib><creatorcontrib>Bergkamp, R.</creatorcontrib><creatorcontrib>Dirkse, W.</creatorcontrib><creatorcontrib>Van Staveren, M.</creatorcontrib><creatorcontrib>Stiekema, W.</creatorcontrib><creatorcontrib>Drost, L.</creatorcontrib><creatorcontrib>Ridley, P.</creatorcontrib><creatorcontrib>Hudson, S.-A.</creatorcontrib><creatorcontrib>Patel, K.</creatorcontrib><creatorcontrib>Murphy, G.</creatorcontrib><creatorcontrib>Piffanelli, P.</creatorcontrib><creatorcontrib>Wedler, H.</creatorcontrib><creatorcontrib>Wedler, E.</creatorcontrib><creatorcontrib>Wambutt, R.</creatorcontrib><creatorcontrib>Weitzenegger, T.</creatorcontrib><creatorcontrib>Pohl, T. M.</creatorcontrib><creatorcontrib>Terryn, N.</creatorcontrib><creatorcontrib>Gielen, J.</creatorcontrib><creatorcontrib>Villarroel, R.</creatorcontrib><creatorcontrib>De Clerck, R.</creatorcontrib><creatorcontrib>Van Montagu, M.</creatorcontrib><creatorcontrib>Lecharny, A.</creatorcontrib><creatorcontrib>Auborg, S.</creatorcontrib><creatorcontrib>Gy, I.</creatorcontrib><creatorcontrib>Kreis, M.</creatorcontrib><creatorcontrib>Lao, N.</creatorcontrib><creatorcontrib>Kavanagh, T.</creatorcontrib><creatorcontrib>Hempel, S.</creatorcontrib><creatorcontrib>Kotter, P.</creatorcontrib><creatorcontrib>Entian, K.-D.</creatorcontrib><creatorcontrib>Rieger, M.</creatorcontrib><creatorcontrib>Schaeffer, M.</creatorcontrib><creatorcontrib>Funk, B.</creatorcontrib><creatorcontrib>Mueller-Auer, S.</creatorcontrib><creatorcontrib>Silvey, M.</creatorcontrib><creatorcontrib>James, R.</creatorcontrib><creatorcontrib>Montfort, A.</creatorcontrib><creatorcontrib>Pons, A.</creatorcontrib><creatorcontrib>Puigdomenech, P.</creatorcontrib><creatorcontrib>Douka, A.</creatorcontrib><creatorcontrib>Voukelatou, E.</creatorcontrib><creatorcontrib>Milioni, D.</creatorcontrib><creatorcontrib>Hatzopoulos, P.</creatorcontrib><creatorcontrib>Piravandi, E.</creatorcontrib><creatorcontrib>Obermaier, B.</creatorcontrib><creatorcontrib>Hilbert, H.</creatorcontrib><creatorcontrib>Düsterhöft, A.</creatorcontrib><creatorcontrib>Moores, T.</creatorcontrib><creatorcontrib>Jones, J. D. G.</creatorcontrib><creatorcontrib>Eneva, T.</creatorcontrib><creatorcontrib>Palme, K.</creatorcontrib><creatorcontrib>Benes, V.</creatorcontrib><creatorcontrib>Rechman, S.</creatorcontrib><creatorcontrib>Ansorge, W.</creatorcontrib><creatorcontrib>Cooke, R.</creatorcontrib><creatorcontrib>Berger, C.</creatorcontrib><creatorcontrib>Delseny, M.</creatorcontrib><creatorcontrib>Voet, M.</creatorcontrib><creatorcontrib>Volckaert, G.</creatorcontrib><creatorcontrib>Mewes, H.-W.</creatorcontrib><creatorcontrib>Klosterman, S.</creatorcontrib><creatorcontrib>Schueller, C.</creatorcontrib><creatorcontrib>Chalwatzis, N.</creatorcontrib><title>Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis thaliana</title><title>Nature (London)</title><addtitle>Nature</addtitle><addtitle>Nature</addtitle><description>The plant Arabidopsis thaliana (Arabidopsis) has become an important model species for the study of many aspects of plant biology 1 . The relatively small size of the nuclear genome and the availability of extensive physical maps of the five chromosomes 2 , 3 , 4 provide a feasible basis for initiating sequencing of the five chromosomes. The YAC (yeast artificial chromosome)-based physical map of chromosome 4 was used to construct a sequence-ready map of cosmid and BAC (bacterial artificial chromosome) clones covering a 1.9-megabase (Mb) contiguous region 5 , and the sequence of this region is reported here. Analysis of the sequence revealed an average gene density of one gene every 4.8 kilobases (kb), and 54% of the predicted genes had significant similarity to known genes. Other interesting features were found, such as the sequence of a disease-resistance gene locus, the distribution of retroelements, the frequent occurrence of clustered gene families, and the sequence of several classes of genes not previously encountered in plants.</description><subject>Arabidopsis - genetics</subject><subject>Biological and medical sciences</subject><subject>Chromosome Mapping</subject><subject>Chromosomes</subject><subject>Chromosomes, Artificial, Yeast</subject><subject>Classical genetics, quantitative genetics, hybrids</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Genes</subject><subject>Genes, Plant - physiology</subject><subject>Genetics</subject><subject>Genetics of eukaryotes. Biological and molecular evolution</subject><subject>Genome, Plant</subject><subject>Humanities and Social Sciences</subject><subject>letter</subject><subject>Life Sciences</subject><subject>multidisciplinary</subject><subject>Multigene Family</subject><subject>Plant Proteins - genetics</subject><subject>Pteridophyta, spermatophyta</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Sequence Analysis, DNA</subject><subject>Vegetals</subject><subject>Weeds</subject><subject>Yeasts</subject><issn>0028-0836</issn><issn>1476-4687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkc1u1DAUhS0EKkPpIyBFiB-xSLnX_1mOKqBIg9jQtWU7TpsqiQd7gtQdW16TJ8FhRlPBAja25fvp3HvuIeQM4RyB6bdMIIcHZIVcyZpLrR6SFQDVNWgmH5MnOd8CgEDFT8hJwyVSFCtytZ7scJf7XMWuwvPm5_cfn9zy9nHa9ddznHOVw9c5TD5UXYpj5W_KGXMcQ8UXcJ2s69u4XTR2N3bo7WSfkkedHXI4O9yn5Or9uy8Xl_Xm84ePF-tN7QWlu9q1kiI66yz3KgirPDRdI7ji3gXrREDaAnbegvNWtMBagS061lFXIEXZKXmz1y19zTb1o013JtreXK43ZvkDzoE2qL9hYV_t2W2KxU_embHPPgyDnUJxaVQjtUBYwNf_BjlT0GjN_yuJkkrGtSzg87_A2zinsvlsaBlRihJHgV7uIZ9izil0R0cIZonY_I64cM8OYrMbQ3ukDpmW-otD3WZvhy7Zyff5iJWNM1TifvhcKtN1SPcz_dnvF9mMt0A</recordid><startdate>19980129</startdate><enddate>19980129</enddate><creator>The EU Arabidopsis Genome Project</creator><creator>Bevan, M.</creator><creator>Bancroft, I.</creator><creator>Bent, E.</creator><creator>Love, K.</creator><creator>Goodman, H.</creator><creator>Dean, C.</creator><creator>Bergkamp, R.</creator><creator>Dirkse, W.</creator><creator>Van Staveren, M.</creator><creator>Stiekema, W.</creator><creator>Drost, L.</creator><creator>Ridley, P.</creator><creator>Hudson, S.-A.</creator><creator>Patel, K.</creator><creator>Murphy, G.</creator><creator>Piffanelli, P.</creator><creator>Wedler, H.</creator><creator>Wedler, E.</creator><creator>Wambutt, R.</creator><creator>Weitzenegger, T.</creator><creator>Pohl, T. M.</creator><creator>Terryn, N.</creator><creator>Gielen, J.</creator><creator>Villarroel, R.</creator><creator>De Clerck, R.</creator><creator>Van Montagu, M.</creator><creator>Lecharny, A.</creator><creator>Auborg, S.</creator><creator>Gy, I.</creator><creator>Kreis, M.</creator><creator>Lao, N.</creator><creator>Kavanagh, T.</creator><creator>Hempel, S.</creator><creator>Kotter, P.</creator><creator>Entian, K.-D.</creator><creator>Rieger, M.</creator><creator>Schaeffer, M.</creator><creator>Funk, B.</creator><creator>Mueller-Auer, S.</creator><creator>Silvey, M.</creator><creator>James, R.</creator><creator>Montfort, A.</creator><creator>Pons, A.</creator><creator>Puigdomenech, P.</creator><creator>Douka, A.</creator><creator>Voukelatou, E.</creator><creator>Milioni, D.</creator><creator>Hatzopoulos, P.</creator><creator>Piravandi, E.</creator><creator>Obermaier, B.</creator><creator>Hilbert, H.</creator><creator>Düsterhöft, A.</creator><creator>Moores, T.</creator><creator>Jones, J. D. G.</creator><creator>Eneva, T.</creator><creator>Palme, K.</creator><creator>Benes, V.</creator><creator>Rechman, S.</creator><creator>Ansorge, W.</creator><creator>Cooke, R.</creator><creator>Berger, C.</creator><creator>Delseny, M.</creator><creator>Voet, M.</creator><creator>Volckaert, G.</creator><creator>Mewes, H.-W.</creator><creator>Klosterman, S.</creator><creator>Schueller, C.</creator><creator>Chalwatzis, N.</creator><general>Nature Publishing Group UK</general><general>Nature Publishing</general><general>Nature Publishing Group</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QP</scope><scope>7QR</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7ST</scope><scope>7T5</scope><scope>7TG</scope><scope>7TK</scope><scope>7TM</scope><scope>7TO</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88G</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>BKSAR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PCBAR</scope><scope>PDBOC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>Q9U</scope><scope>R05</scope><scope>RC3</scope><scope>S0X</scope><scope>SOI</scope><scope>7SC</scope><scope>7SP</scope><scope>7SR</scope><scope>7TB</scope><scope>7U5</scope><scope>8BQ</scope><scope>F28</scope><scope>JG9</scope><scope>JQ2</scope><scope>KR7</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>7X8</scope><scope>1XC</scope><orcidid>https://orcid.org/0000-0002-0695-4767</orcidid></search><sort><creationdate>19980129</creationdate><title>Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis thaliana</title><author>The EU Arabidopsis Genome Project ; Bevan, M. ; Bancroft, I. ; Bent, E. ; Love, K. ; Goodman, H. ; Dean, C. ; Bergkamp, R. ; Dirkse, W. ; Van Staveren, M. ; Stiekema, W. ; Drost, L. ; Ridley, P. ; Hudson, S.-A. ; Patel, K. ; Murphy, G. ; Piffanelli, P. ; Wedler, H. ; Wedler, E. ; Wambutt, R. ; Weitzenegger, T. ; Pohl, T. M. ; Terryn, N. ; Gielen, J. ; Villarroel, R. ; De Clerck, R. ; Van Montagu, M. ; Lecharny, A. ; Auborg, S. ; Gy, I. ; Kreis, M. ; Lao, N. ; Kavanagh, T. ; Hempel, S. ; Kotter, P. ; Entian, K.-D. ; Rieger, M. ; Schaeffer, M. ; Funk, B. ; Mueller-Auer, S. ; Silvey, M. ; James, R. ; Montfort, A. ; Pons, A. ; Puigdomenech, P. ; Douka, A. ; Voukelatou, E. ; Milioni, D. ; Hatzopoulos, P. ; Piravandi, E. ; Obermaier, B. ; Hilbert, H. ; Düsterhöft, A. ; Moores, T. ; Jones, J. D. G. ; Eneva, T. ; Palme, K. ; Benes, V. ; Rechman, S. ; Ansorge, W. ; Cooke, R. ; Berger, C. ; Delseny, M. ; Voet, M. ; Volckaert, G. ; Mewes, H.-W. ; Klosterman, S. ; Schueller, C. ; Chalwatzis, N.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c522t-bd6211baba4c7e5a7c09f95474cbeab5e12d01fca0bca5d03d51d1b3f2b547723</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Arabidopsis - genetics</topic><topic>Biological and medical sciences</topic><topic>Chromosome Mapping</topic><topic>Chromosomes</topic><topic>Chromosomes, Artificial, Yeast</topic><topic>Classical genetics, quantitative genetics, hybrids</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Genes</topic><topic>Genes, Plant - physiology</topic><topic>Genetics</topic><topic>Genetics of eukaryotes. Biological and molecular evolution</topic><topic>Genome, Plant</topic><topic>Humanities and Social Sciences</topic><topic>letter</topic><topic>Life Sciences</topic><topic>multidisciplinary</topic><topic>Multigene Family</topic><topic>Plant Proteins - genetics</topic><topic>Pteridophyta, spermatophyta</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><topic>Sequence Analysis, DNA</topic><topic>Vegetals</topic><topic>Weeds</topic><topic>Yeasts</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>The EU Arabidopsis Genome Project</creatorcontrib><creatorcontrib>Bevan, M.</creatorcontrib><creatorcontrib>Bancroft, I.</creatorcontrib><creatorcontrib>Bent, E.</creatorcontrib><creatorcontrib>Love, K.</creatorcontrib><creatorcontrib>Goodman, H.</creatorcontrib><creatorcontrib>Dean, C.</creatorcontrib><creatorcontrib>Bergkamp, R.</creatorcontrib><creatorcontrib>Dirkse, W.</creatorcontrib><creatorcontrib>Van Staveren, M.</creatorcontrib><creatorcontrib>Stiekema, W.</creatorcontrib><creatorcontrib>Drost, L.</creatorcontrib><creatorcontrib>Ridley, P.</creatorcontrib><creatorcontrib>Hudson, S.-A.</creatorcontrib><creatorcontrib>Patel, K.</creatorcontrib><creatorcontrib>Murphy, G.</creatorcontrib><creatorcontrib>Piffanelli, P.</creatorcontrib><creatorcontrib>Wedler, H.</creatorcontrib><creatorcontrib>Wedler, E.</creatorcontrib><creatorcontrib>Wambutt, R.</creatorcontrib><creatorcontrib>Weitzenegger, T.</creatorcontrib><creatorcontrib>Pohl, T. M.</creatorcontrib><creatorcontrib>Terryn, N.</creatorcontrib><creatorcontrib>Gielen, J.</creatorcontrib><creatorcontrib>Villarroel, R.</creatorcontrib><creatorcontrib>De Clerck, R.</creatorcontrib><creatorcontrib>Van Montagu, M.</creatorcontrib><creatorcontrib>Lecharny, A.</creatorcontrib><creatorcontrib>Auborg, S.</creatorcontrib><creatorcontrib>Gy, I.</creatorcontrib><creatorcontrib>Kreis, M.</creatorcontrib><creatorcontrib>Lao, N.</creatorcontrib><creatorcontrib>Kavanagh, T.</creatorcontrib><creatorcontrib>Hempel, S.</creatorcontrib><creatorcontrib>Kotter, P.</creatorcontrib><creatorcontrib>Entian, K.-D.</creatorcontrib><creatorcontrib>Rieger, M.</creatorcontrib><creatorcontrib>Schaeffer, M.</creatorcontrib><creatorcontrib>Funk, B.</creatorcontrib><creatorcontrib>Mueller-Auer, S.</creatorcontrib><creatorcontrib>Silvey, M.</creatorcontrib><creatorcontrib>James, R.</creatorcontrib><creatorcontrib>Montfort, A.</creatorcontrib><creatorcontrib>Pons, A.</creatorcontrib><creatorcontrib>Puigdomenech, P.</creatorcontrib><creatorcontrib>Douka, A.</creatorcontrib><creatorcontrib>Voukelatou, E.</creatorcontrib><creatorcontrib>Milioni, D.</creatorcontrib><creatorcontrib>Hatzopoulos, P.</creatorcontrib><creatorcontrib>Piravandi, E.</creatorcontrib><creatorcontrib>Obermaier, B.</creatorcontrib><creatorcontrib>Hilbert, H.</creatorcontrib><creatorcontrib>Düsterhöft, A.</creatorcontrib><creatorcontrib>Moores, T.</creatorcontrib><creatorcontrib>Jones, J. D. G.</creatorcontrib><creatorcontrib>Eneva, T.</creatorcontrib><creatorcontrib>Palme, K.</creatorcontrib><creatorcontrib>Benes, V.</creatorcontrib><creatorcontrib>Rechman, S.</creatorcontrib><creatorcontrib>Ansorge, W.</creatorcontrib><creatorcontrib>Cooke, R.</creatorcontrib><creatorcontrib>Berger, C.</creatorcontrib><creatorcontrib>Delseny, M.</creatorcontrib><creatorcontrib>Voet, M.</creatorcontrib><creatorcontrib>Volckaert, G.</creatorcontrib><creatorcontrib>Mewes, H.-W.</creatorcontrib><creatorcontrib>Klosterman, S.</creatorcontrib><creatorcontrib>Schueller, C.</creatorcontrib><creatorcontrib>Chalwatzis, N.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Nursing & Allied Health Database (ProQuest)</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Environment Abstracts</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection (Proquest)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database (ProQuest Medical & Health Databases)</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Database‎ (1962 - current)</collection><collection>ProQuest Agriculture & Environmental Science Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Earth, Atmospheric & Aquatic Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>Biological Sciences</collection><collection>Agriculture Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Psychology Database (ProQuest)</collection><collection>ProQuest Research Library</collection><collection>Science Database (ProQuest)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>ProQuest Engineering Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest advanced technologies & aerospace journals</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>ProQuest Earth, Atmospheric & Aquatic Science Database</collection><collection>Materials Science Collection</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest One Psychology</collection><collection>Engineering collection</collection><collection>Environmental Science Collection</collection><collection>ProQuest Central Basic</collection><collection>University of Michigan</collection><collection>Genetics Abstracts</collection><collection>SIRS Editorial</collection><collection>Environment Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Materials Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>Civil Engineering Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>Nature (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>The EU Arabidopsis Genome Project</au><au>Bevan, M.</au><au>Bancroft, I.</au><au>Bent, E.</au><au>Love, K.</au><au>Goodman, H.</au><au>Dean, C.</au><au>Bergkamp, R.</au><au>Dirkse, W.</au><au>Van Staveren, M.</au><au>Stiekema, W.</au><au>Drost, L.</au><au>Ridley, P.</au><au>Hudson, S.-A.</au><au>Patel, K.</au><au>Murphy, G.</au><au>Piffanelli, P.</au><au>Wedler, H.</au><au>Wedler, E.</au><au>Wambutt, R.</au><au>Weitzenegger, T.</au><au>Pohl, T. M.</au><au>Terryn, N.</au><au>Gielen, J.</au><au>Villarroel, R.</au><au>De Clerck, R.</au><au>Van Montagu, M.</au><au>Lecharny, A.</au><au>Auborg, S.</au><au>Gy, I.</au><au>Kreis, M.</au><au>Lao, N.</au><au>Kavanagh, T.</au><au>Hempel, S.</au><au>Kotter, P.</au><au>Entian, K.-D.</au><au>Rieger, M.</au><au>Schaeffer, M.</au><au>Funk, B.</au><au>Mueller-Auer, S.</au><au>Silvey, M.</au><au>James, R.</au><au>Montfort, A.</au><au>Pons, A.</au><au>Puigdomenech, P.</au><au>Douka, A.</au><au>Voukelatou, E.</au><au>Milioni, D.</au><au>Hatzopoulos, P.</au><au>Piravandi, E.</au><au>Obermaier, B.</au><au>Hilbert, H.</au><au>Düsterhöft, A.</au><au>Moores, T.</au><au>Jones, J. D. G.</au><au>Eneva, T.</au><au>Palme, K.</au><au>Benes, V.</au><au>Rechman, S.</au><au>Ansorge, W.</au><au>Cooke, R.</au><au>Berger, C.</au><au>Delseny, M.</au><au>Voet, M.</au><au>Volckaert, G.</au><au>Mewes, H.-W.</au><au>Klosterman, S.</au><au>Schueller, C.</au><au>Chalwatzis, N.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis thaliana</atitle><jtitle>Nature (London)</jtitle><stitle>Nature</stitle><addtitle>Nature</addtitle><date>1998-01-29</date><risdate>1998</risdate><volume>391</volume><issue>6666</issue><spage>485</spage><epage>488</epage><pages>485-488</pages><issn>0028-0836</issn><eissn>1476-4687</eissn><coden>NATUAS</coden><abstract>The plant Arabidopsis thaliana (Arabidopsis) has become an important model species for the study of many aspects of plant biology 1 . The relatively small size of the nuclear genome and the availability of extensive physical maps of the five chromosomes 2 , 3 , 4 provide a feasible basis for initiating sequencing of the five chromosomes. The YAC (yeast artificial chromosome)-based physical map of chromosome 4 was used to construct a sequence-ready map of cosmid and BAC (bacterial artificial chromosome) clones covering a 1.9-megabase (Mb) contiguous region 5 , and the sequence of this region is reported here. Analysis of the sequence revealed an average gene density of one gene every 4.8 kilobases (kb), and 54% of the predicted genes had significant similarity to known genes. Other interesting features were found, such as the sequence of a disease-resistance gene locus, the distribution of retroelements, the frequent occurrence of clustered gene families, and the sequence of several classes of genes not previously encountered in plants.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>9461215</pmid><doi>10.1038/35140</doi><tpages>4</tpages><orcidid>https://orcid.org/0000-0002-0695-4767</orcidid></addata></record>
fulltext	fulltext
identifier	ISSN: 0028-0836
ispartof	Nature (London), 1998-01, Vol.391 (6666), p.485-488
issn	0028-0836 1476-4687
language	eng
recordid	cdi_hal_primary_oai_HAL_hal_04402918v1
source	MEDLINE; Springer Online Journals; Springer Nature - Connect here FIRST to enable access
subjects	Arabidopsis - genetics Biological and medical sciences Chromosome Mapping Chromosomes Chromosomes, Artificial, Yeast Classical genetics, quantitative genetics, hybrids Fundamental and applied biological sciences. Psychology Genes Genes, Plant - physiology Genetics Genetics of eukaryotes. Biological and molecular evolution Genome, Plant Humanities and Social Sciences letter Life Sciences multidisciplinary Multigene Family Plant Proteins - genetics Pteridophyta, spermatophyta Science Science (multidisciplinary) Sequence Analysis, DNA Vegetals Weeds Yeasts
title	Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis thaliana
url	https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-14T15%3A03%3A41IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_hal_p&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Analysis%20of%201.9%E2%80%89Mb%20of%20contiguous%20sequence%20from%20chromosome%204%20of%20Arabidopsis%20thaliana&rft.jtitle=Nature%20(London)&rft.au=The%20EU%20Arabidopsis%20Genome%20Project&rft.date=1998-01-29&rft.volume=391&rft.issue=6666&rft.spage=485&rft.epage=488&rft.pages=485-488&rft.issn=0028-0836&rft.eissn=1476-4687&rft.coden=NATUAS&rft_id=info:doi/10.1038/35140&rft_dat=%3Cproquest_hal_p%3E743709884%3C/proquest_hal_p%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=204465461&rft_id=info:pmid/9461215&rfr_iscdi=true