Direct Aortic Versus Supra-Aortic Arterial Cannulation During Surgery for Acute Type A Aortic Dissection

Aims In this study we evaluated the impact of direct aortic cannulation versus innominate/subclavian/axillary artery cannulation on the outcome after surgery for type A aortic dissection. Methods The outcomes of patients included in a multicenter European registry (ERTAAD) who underwent surgery for...

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Veröffentlicht in:World journal of surgery 2023-11, Vol.47 (11), p.2899-2908
Hauptverfasser: Juvonen, Tatu, Jormalainen, Mikko, Mustonen, Caius, Demal, Till, Fiore, Antonio, Perrotti, Andrea, Hervé, Amélie, Mazzaro, Enzo, Gatti, Giuseppe, Pettinari, Matteo, Peterss, Sven, Buech, Joscha, Nappi, Francesco, Conradi, Lenard, Pinto, Angel G., Rodriguez Lega, Javier, Pol, Marek, Kacer, Petr, Dell’Aquila, Angelo M., Rukosujew, Andreas, Wisniewski, Konrad, Vendramin, Igor, Piani, Daniela, Ferrante, Luisa, Rinaldi, Mauro, Quintana, Eduard, Pruna-Guillen, Robert, Gerelli, Sebastien, Di Perna, Dario, Folliguet, Thierry, Acharya, Metesh, Field, Mark, Kuduvalli, Manoj, Onorati, Francesco, Rossetti, Cecilia, Mäkikallio, Timo, Raivio, Peter, Mariscalco, Giovanni, Biancari, Fausto
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container_end_page 2908
container_issue 11
container_start_page 2899
container_title World journal of surgery
container_volume 47
creator Juvonen, Tatu
Jormalainen, Mikko
Mustonen, Caius
Demal, Till
Fiore, Antonio
Perrotti, Andrea
Hervé, Amélie
Mazzaro, Enzo
Gatti, Giuseppe
Pettinari, Matteo
Peterss, Sven
Buech, Joscha
Nappi, Francesco
Conradi, Lenard
Pinto, Angel G.
Rodriguez Lega, Javier
Pol, Marek
Kacer, Petr
Dell’Aquila, Angelo M.
Rukosujew, Andreas
Wisniewski, Konrad
Vendramin, Igor
Piani, Daniela
Ferrante, Luisa
Rinaldi, Mauro
Quintana, Eduard
Pruna-Guillen, Robert
Gerelli, Sebastien
Di Perna, Dario
Folliguet, Thierry
Acharya, Metesh
Field, Mark
Kuduvalli, Manoj
Onorati, Francesco
Rossetti, Cecilia
Mäkikallio, Timo
Raivio, Peter
Mariscalco, Giovanni
Biancari, Fausto
description Aims In this study we evaluated the impact of direct aortic cannulation versus innominate/subclavian/axillary artery cannulation on the outcome after surgery for type A aortic dissection. Methods The outcomes of patients included in a multicenter European registry (ERTAAD) who underwent surgery for acute type A aortic dissection with direct aortic cannulation versus those with innominate/subclavian/axillary artery cannulation, i.e. supra-aortic arterial cannulation, were compared using propensity score matched analysis. Results Out of 3902 consecutive patients included in the registry, 2478 (63.5%) patients were eligible for this analysis. Direct aortic cannulation was performed in 627 (25.3%) patients, while supra-aortic arterial cannulation in 1851 (74.7%) patients. Propensity score matching yielded 614 pairs of patients. Among them, patients who underwent surgery for TAAD with direct aortic cannulation had significantly decreased in-hospital mortality (12.7% vs. 18.1%, p  = 0.009) compared to those who had supra-aortic arterial cannulation. Furthermore, direct aortic cannulation was associated with decreased postoperative rates of paraparesis/paraplegia (2.0 vs. 6.0%, p  
doi_str_mv 10.1007/s00268-023-07116-z
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Methods The outcomes of patients included in a multicenter European registry (ERTAAD) who underwent surgery for acute type A aortic dissection with direct aortic cannulation versus those with innominate/subclavian/axillary artery cannulation, i.e. supra-aortic arterial cannulation, were compared using propensity score matched analysis. Results Out of 3902 consecutive patients included in the registry, 2478 (63.5%) patients were eligible for this analysis. Direct aortic cannulation was performed in 627 (25.3%) patients, while supra-aortic arterial cannulation in 1851 (74.7%) patients. Propensity score matching yielded 614 pairs of patients. Among them, patients who underwent surgery for TAAD with direct aortic cannulation had significantly decreased in-hospital mortality (12.7% vs. 18.1%, p  = 0.009) compared to those who had supra-aortic arterial cannulation. Furthermore, direct aortic cannulation was associated with decreased postoperative rates of paraparesis/paraplegia (2.0 vs. 6.0%, p  &lt; 0.0001), mesenteric ischemia (1.8 vs. 5.1%, p  = 0.002), sepsis (7.0 vs. 14.2%, p  &lt; 0.0001), heart failure (11.2 vs. 15.2%, p  = 0.043), and major lower limb amputation (0 vs. 1.0%, p  = 0.031). Direct aortic cannulation showed a trend toward decreased risk of postoperative dialysis (10.1 vs. 13.7%, p  = 0.051). Conclusions This multicenter cohort study showed that direct aortic cannulation compared to supra-aortic arterial cannulation is associated with a significant reduction of the risk of in-hospital mortality after surgery for acute type A aortic dissection. Trial registration ClinicalTrials.gov Identifier: NCT04831073.</description><identifier>ISSN: 0364-2313</identifier><identifier>EISSN: 1432-2323</identifier><identifier>DOI: 10.1007/s00268-023-07116-z</identifier><identifier>PMID: 37432422</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Abdominal Surgery ; Amputation ; Aorta ; Aortic dissection ; Cannulation ; Cardiac Surgery ; Congestive heart failure ; Dialysis ; Dissection ; General Surgery ; Hospitals ; Ischemia ; Life Sciences ; Medicine ; Medicine &amp; Public Health ; Mortality ; Original Scientific Report ; Paraplegia ; Paraplegics ; Patients ; Sepsis ; Surgery ; Thoracic Surgery ; Vascular Surgery</subject><ispartof>World journal of surgery, 2023-11, Vol.47 (11), p.2899-2908</ispartof><rights>The Author(s) under exclusive licence to Société Internationale de Chirurgie 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><rights>2023 The Author(s) under exclusive licence to Société Internationale de Chirurgie</rights><rights>2023. The Author(s) under exclusive licence to Société Internationale de Chirurgie.</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4604-d8e4f9d96e4015901109bc8ab51f6f70f0c7156466660d9896fef285b775724f3</citedby><cites>FETCH-LOGICAL-c4604-d8e4f9d96e4015901109bc8ab51f6f70f0c7156466660d9896fef285b775724f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00268-023-07116-z$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00268-023-07116-z$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,315,782,786,887,1419,27933,27934,41497,42566,45583,45584,51328</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37432422$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-04389496$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Juvonen, Tatu</creatorcontrib><creatorcontrib>Jormalainen, Mikko</creatorcontrib><creatorcontrib>Mustonen, Caius</creatorcontrib><creatorcontrib>Demal, Till</creatorcontrib><creatorcontrib>Fiore, Antonio</creatorcontrib><creatorcontrib>Perrotti, Andrea</creatorcontrib><creatorcontrib>Hervé, Amélie</creatorcontrib><creatorcontrib>Mazzaro, Enzo</creatorcontrib><creatorcontrib>Gatti, Giuseppe</creatorcontrib><creatorcontrib>Pettinari, Matteo</creatorcontrib><creatorcontrib>Peterss, Sven</creatorcontrib><creatorcontrib>Buech, Joscha</creatorcontrib><creatorcontrib>Nappi, Francesco</creatorcontrib><creatorcontrib>Conradi, Lenard</creatorcontrib><creatorcontrib>Pinto, Angel G.</creatorcontrib><creatorcontrib>Rodriguez Lega, Javier</creatorcontrib><creatorcontrib>Pol, Marek</creatorcontrib><creatorcontrib>Kacer, Petr</creatorcontrib><creatorcontrib>Dell’Aquila, Angelo M.</creatorcontrib><creatorcontrib>Rukosujew, Andreas</creatorcontrib><creatorcontrib>Wisniewski, Konrad</creatorcontrib><creatorcontrib>Vendramin, Igor</creatorcontrib><creatorcontrib>Piani, Daniela</creatorcontrib><creatorcontrib>Ferrante, Luisa</creatorcontrib><creatorcontrib>Rinaldi, Mauro</creatorcontrib><creatorcontrib>Quintana, Eduard</creatorcontrib><creatorcontrib>Pruna-Guillen, Robert</creatorcontrib><creatorcontrib>Gerelli, Sebastien</creatorcontrib><creatorcontrib>Di Perna, Dario</creatorcontrib><creatorcontrib>Folliguet, Thierry</creatorcontrib><creatorcontrib>Acharya, Metesh</creatorcontrib><creatorcontrib>Field, Mark</creatorcontrib><creatorcontrib>Kuduvalli, Manoj</creatorcontrib><creatorcontrib>Onorati, Francesco</creatorcontrib><creatorcontrib>Rossetti, Cecilia</creatorcontrib><creatorcontrib>Mäkikallio, Timo</creatorcontrib><creatorcontrib>Raivio, Peter</creatorcontrib><creatorcontrib>Mariscalco, Giovanni</creatorcontrib><creatorcontrib>Biancari, Fausto</creatorcontrib><title>Direct Aortic Versus Supra-Aortic Arterial Cannulation During Surgery for Acute Type A Aortic Dissection</title><title>World journal of surgery</title><addtitle>World J Surg</addtitle><addtitle>World J Surg</addtitle><description>Aims In this study we evaluated the impact of direct aortic cannulation versus innominate/subclavian/axillary artery cannulation on the outcome after surgery for type A aortic dissection. Methods The outcomes of patients included in a multicenter European registry (ERTAAD) who underwent surgery for acute type A aortic dissection with direct aortic cannulation versus those with innominate/subclavian/axillary artery cannulation, i.e. supra-aortic arterial cannulation, were compared using propensity score matched analysis. Results Out of 3902 consecutive patients included in the registry, 2478 (63.5%) patients were eligible for this analysis. Direct aortic cannulation was performed in 627 (25.3%) patients, while supra-aortic arterial cannulation in 1851 (74.7%) patients. Propensity score matching yielded 614 pairs of patients. Among them, patients who underwent surgery for TAAD with direct aortic cannulation had significantly decreased in-hospital mortality (12.7% vs. 18.1%, p  = 0.009) compared to those who had supra-aortic arterial cannulation. Furthermore, direct aortic cannulation was associated with decreased postoperative rates of paraparesis/paraplegia (2.0 vs. 6.0%, p  &lt; 0.0001), mesenteric ischemia (1.8 vs. 5.1%, p  = 0.002), sepsis (7.0 vs. 14.2%, p  &lt; 0.0001), heart failure (11.2 vs. 15.2%, p  = 0.043), and major lower limb amputation (0 vs. 1.0%, p  = 0.031). Direct aortic cannulation showed a trend toward decreased risk of postoperative dialysis (10.1 vs. 13.7%, p  = 0.051). Conclusions This multicenter cohort study showed that direct aortic cannulation compared to supra-aortic arterial cannulation is associated with a significant reduction of the risk of in-hospital mortality after surgery for acute type A aortic dissection. Trial registration ClinicalTrials.gov Identifier: NCT04831073.</description><subject>Abdominal Surgery</subject><subject>Amputation</subject><subject>Aorta</subject><subject>Aortic dissection</subject><subject>Cannulation</subject><subject>Cardiac Surgery</subject><subject>Congestive heart failure</subject><subject>Dialysis</subject><subject>Dissection</subject><subject>General Surgery</subject><subject>Hospitals</subject><subject>Ischemia</subject><subject>Life Sciences</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Mortality</subject><subject>Original Scientific Report</subject><subject>Paraplegia</subject><subject>Paraplegics</subject><subject>Patients</subject><subject>Sepsis</subject><subject>Surgery</subject><subject>Thoracic Surgery</subject><subject>Vascular Surgery</subject><issn>0364-2313</issn><issn>1432-2323</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqNkc1u1DAUhS1ERYeBF2CBLLGBRcr1T-yYXZihtNVILFpgaXkydusqk6R2DJo-PR4yLRILhDe2rr5zdK4PQq8InBAA-T4CUFEVQFkBkhBR3D9BM8IZLSij7CmaARM8vwk7Rs9jvAUgUoB4ho6ZzBSndIZulj7YZsR1H0bf4G82xBTxZRqCKQ6zOow2eNPihem61JrR9x1epuC76wyGaxt22PUB100aLb7aDRbXD35LH2O2z4oX6MiZNtqXh3uOvp5-ulqcFasvn88X9apouABebCrLndooYTmQUgEhoNZNZdYlccJJcNBIUgou8oGNqpRw1tGqXEtZSsodm6N3k--NafUQ_NaEne6N12f1Su9nwFmluBI_SGbfTuwQ-rtk46i3Pja2bU1n-xR19uWclYRWGX3zF3rbp9DlTTIlCa9Kln9-juhENaGPMVj3mICA3nemp8507kz_7kzfZ9Hrg3Vab-3mUfJQUgY-TMBP39rdf1jq7xeXH09BcbaPxCZxHPaN2fAn-D8y_QLR6LEB</recordid><startdate>202311</startdate><enddate>202311</enddate><creator>Juvonen, Tatu</creator><creator>Jormalainen, Mikko</creator><creator>Mustonen, Caius</creator><creator>Demal, Till</creator><creator>Fiore, Antonio</creator><creator>Perrotti, Andrea</creator><creator>Hervé, Amélie</creator><creator>Mazzaro, Enzo</creator><creator>Gatti, Giuseppe</creator><creator>Pettinari, Matteo</creator><creator>Peterss, Sven</creator><creator>Buech, Joscha</creator><creator>Nappi, Francesco</creator><creator>Conradi, Lenard</creator><creator>Pinto, Angel G.</creator><creator>Rodriguez Lega, Javier</creator><creator>Pol, Marek</creator><creator>Kacer, Petr</creator><creator>Dell’Aquila, Angelo M.</creator><creator>Rukosujew, Andreas</creator><creator>Wisniewski, Konrad</creator><creator>Vendramin, Igor</creator><creator>Piani, Daniela</creator><creator>Ferrante, Luisa</creator><creator>Rinaldi, Mauro</creator><creator>Quintana, Eduard</creator><creator>Pruna-Guillen, Robert</creator><creator>Gerelli, Sebastien</creator><creator>Di Perna, Dario</creator><creator>Folliguet, Thierry</creator><creator>Acharya, Metesh</creator><creator>Field, Mark</creator><creator>Kuduvalli, Manoj</creator><creator>Onorati, Francesco</creator><creator>Rossetti, Cecilia</creator><creator>Mäkikallio, Timo</creator><creator>Raivio, Peter</creator><creator>Mariscalco, Giovanni</creator><creator>Biancari, Fausto</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><general>Springer Verlag</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7T5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>1XC</scope></search><sort><creationdate>202311</creationdate><title>Direct Aortic Versus Supra-Aortic Arterial Cannulation During Surgery for Acute Type A Aortic Dissection</title><author>Juvonen, Tatu ; Jormalainen, Mikko ; Mustonen, Caius ; Demal, Till ; Fiore, Antonio ; Perrotti, Andrea ; Hervé, Amélie ; Mazzaro, Enzo ; Gatti, Giuseppe ; Pettinari, Matteo ; Peterss, Sven ; Buech, Joscha ; Nappi, Francesco ; Conradi, Lenard ; Pinto, Angel G. ; Rodriguez Lega, Javier ; Pol, Marek ; Kacer, Petr ; Dell’Aquila, Angelo M. ; Rukosujew, Andreas ; Wisniewski, Konrad ; Vendramin, Igor ; Piani, Daniela ; Ferrante, Luisa ; Rinaldi, Mauro ; Quintana, Eduard ; Pruna-Guillen, Robert ; Gerelli, Sebastien ; Di Perna, Dario ; Folliguet, Thierry ; Acharya, Metesh ; Field, Mark ; Kuduvalli, Manoj ; Onorati, Francesco ; Rossetti, Cecilia ; Mäkikallio, Timo ; Raivio, Peter ; Mariscalco, Giovanni ; Biancari, Fausto</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4604-d8e4f9d96e4015901109bc8ab51f6f70f0c7156466660d9896fef285b775724f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Abdominal Surgery</topic><topic>Amputation</topic><topic>Aorta</topic><topic>Aortic dissection</topic><topic>Cannulation</topic><topic>Cardiac Surgery</topic><topic>Congestive heart failure</topic><topic>Dialysis</topic><topic>Dissection</topic><topic>General Surgery</topic><topic>Hospitals</topic><topic>Ischemia</topic><topic>Life Sciences</topic><topic>Medicine</topic><topic>Medicine &amp; Public Health</topic><topic>Mortality</topic><topic>Original Scientific Report</topic><topic>Paraplegia</topic><topic>Paraplegics</topic><topic>Patients</topic><topic>Sepsis</topic><topic>Surgery</topic><topic>Thoracic Surgery</topic><topic>Vascular Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Juvonen, Tatu</creatorcontrib><creatorcontrib>Jormalainen, Mikko</creatorcontrib><creatorcontrib>Mustonen, Caius</creatorcontrib><creatorcontrib>Demal, Till</creatorcontrib><creatorcontrib>Fiore, Antonio</creatorcontrib><creatorcontrib>Perrotti, Andrea</creatorcontrib><creatorcontrib>Hervé, Amélie</creatorcontrib><creatorcontrib>Mazzaro, Enzo</creatorcontrib><creatorcontrib>Gatti, Giuseppe</creatorcontrib><creatorcontrib>Pettinari, Matteo</creatorcontrib><creatorcontrib>Peterss, Sven</creatorcontrib><creatorcontrib>Buech, Joscha</creatorcontrib><creatorcontrib>Nappi, Francesco</creatorcontrib><creatorcontrib>Conradi, Lenard</creatorcontrib><creatorcontrib>Pinto, Angel G.</creatorcontrib><creatorcontrib>Rodriguez Lega, Javier</creatorcontrib><creatorcontrib>Pol, Marek</creatorcontrib><creatorcontrib>Kacer, Petr</creatorcontrib><creatorcontrib>Dell’Aquila, Angelo M.</creatorcontrib><creatorcontrib>Rukosujew, Andreas</creatorcontrib><creatorcontrib>Wisniewski, Konrad</creatorcontrib><creatorcontrib>Vendramin, Igor</creatorcontrib><creatorcontrib>Piani, Daniela</creatorcontrib><creatorcontrib>Ferrante, Luisa</creatorcontrib><creatorcontrib>Rinaldi, Mauro</creatorcontrib><creatorcontrib>Quintana, Eduard</creatorcontrib><creatorcontrib>Pruna-Guillen, Robert</creatorcontrib><creatorcontrib>Gerelli, Sebastien</creatorcontrib><creatorcontrib>Di Perna, Dario</creatorcontrib><creatorcontrib>Folliguet, Thierry</creatorcontrib><creatorcontrib>Acharya, Metesh</creatorcontrib><creatorcontrib>Field, Mark</creatorcontrib><creatorcontrib>Kuduvalli, Manoj</creatorcontrib><creatorcontrib>Onorati, Francesco</creatorcontrib><creatorcontrib>Rossetti, Cecilia</creatorcontrib><creatorcontrib>Mäkikallio, Timo</creatorcontrib><creatorcontrib>Raivio, Peter</creatorcontrib><creatorcontrib>Mariscalco, Giovanni</creatorcontrib><creatorcontrib>Biancari, Fausto</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Immunology Abstracts</collection><collection>Health &amp; 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Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>World journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Juvonen, Tatu</au><au>Jormalainen, Mikko</au><au>Mustonen, Caius</au><au>Demal, Till</au><au>Fiore, Antonio</au><au>Perrotti, Andrea</au><au>Hervé, Amélie</au><au>Mazzaro, Enzo</au><au>Gatti, Giuseppe</au><au>Pettinari, Matteo</au><au>Peterss, Sven</au><au>Buech, Joscha</au><au>Nappi, Francesco</au><au>Conradi, Lenard</au><au>Pinto, Angel G.</au><au>Rodriguez Lega, Javier</au><au>Pol, Marek</au><au>Kacer, Petr</au><au>Dell’Aquila, Angelo M.</au><au>Rukosujew, Andreas</au><au>Wisniewski, Konrad</au><au>Vendramin, Igor</au><au>Piani, Daniela</au><au>Ferrante, Luisa</au><au>Rinaldi, Mauro</au><au>Quintana, Eduard</au><au>Pruna-Guillen, Robert</au><au>Gerelli, Sebastien</au><au>Di Perna, Dario</au><au>Folliguet, Thierry</au><au>Acharya, Metesh</au><au>Field, Mark</au><au>Kuduvalli, Manoj</au><au>Onorati, Francesco</au><au>Rossetti, Cecilia</au><au>Mäkikallio, Timo</au><au>Raivio, Peter</au><au>Mariscalco, Giovanni</au><au>Biancari, Fausto</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Direct Aortic Versus Supra-Aortic Arterial Cannulation During Surgery for Acute Type A Aortic Dissection</atitle><jtitle>World journal of surgery</jtitle><stitle>World J Surg</stitle><addtitle>World J Surg</addtitle><date>2023-11</date><risdate>2023</risdate><volume>47</volume><issue>11</issue><spage>2899</spage><epage>2908</epage><pages>2899-2908</pages><issn>0364-2313</issn><eissn>1432-2323</eissn><abstract>Aims In this study we evaluated the impact of direct aortic cannulation versus innominate/subclavian/axillary artery cannulation on the outcome after surgery for type A aortic dissection. Methods The outcomes of patients included in a multicenter European registry (ERTAAD) who underwent surgery for acute type A aortic dissection with direct aortic cannulation versus those with innominate/subclavian/axillary artery cannulation, i.e. supra-aortic arterial cannulation, were compared using propensity score matched analysis. Results Out of 3902 consecutive patients included in the registry, 2478 (63.5%) patients were eligible for this analysis. Direct aortic cannulation was performed in 627 (25.3%) patients, while supra-aortic arterial cannulation in 1851 (74.7%) patients. Propensity score matching yielded 614 pairs of patients. Among them, patients who underwent surgery for TAAD with direct aortic cannulation had significantly decreased in-hospital mortality (12.7% vs. 18.1%, p  = 0.009) compared to those who had supra-aortic arterial cannulation. Furthermore, direct aortic cannulation was associated with decreased postoperative rates of paraparesis/paraplegia (2.0 vs. 6.0%, p  &lt; 0.0001), mesenteric ischemia (1.8 vs. 5.1%, p  = 0.002), sepsis (7.0 vs. 14.2%, p  &lt; 0.0001), heart failure (11.2 vs. 15.2%, p  = 0.043), and major lower limb amputation (0 vs. 1.0%, p  = 0.031). Direct aortic cannulation showed a trend toward decreased risk of postoperative dialysis (10.1 vs. 13.7%, p  = 0.051). Conclusions This multicenter cohort study showed that direct aortic cannulation compared to supra-aortic arterial cannulation is associated with a significant reduction of the risk of in-hospital mortality after surgery for acute type A aortic dissection. Trial registration ClinicalTrials.gov Identifier: NCT04831073.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>37432422</pmid><doi>10.1007/s00268-023-07116-z</doi><tpages>10</tpages></addata></record>
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identifier ISSN: 0364-2313
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issn 0364-2313
1432-2323
language eng
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source SpringerNature Journals; Access via Wiley Online Library
subjects Abdominal Surgery
Amputation
Aorta
Aortic dissection
Cannulation
Cardiac Surgery
Congestive heart failure
Dialysis
Dissection
General Surgery
Hospitals
Ischemia
Life Sciences
Medicine
Medicine & Public Health
Mortality
Original Scientific Report
Paraplegia
Paraplegics
Patients
Sepsis
Surgery
Thoracic Surgery
Vascular Surgery
title Direct Aortic Versus Supra-Aortic Arterial Cannulation During Surgery for Acute Type A Aortic Dissection
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