Signature of functional enzyme dynamics in quasielastic neutron scattering spectra: The case of phosphoglycerate kinase

We present an analysis of high-resolution quasi-elastic neutron scattering spectra of phosphoglycerate kinase which elucidates the influence of the enzymatic activity on the dynamics of the protein. We show that in the active state the inter-domain motions are amplified and the intra-domain asymptot...

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Veröffentlicht in:	The Journal of chemical physics 2023-10, Vol.159 (14)
Hauptverfasser:	Hassani, Abir N., Haris, Luman, Appel, Markus, Seydel, Tilo, Stadler, Andreas M., Kneller, Gerald R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Condensed Matter Elastic scattering Energy distribution Kinases Neutron scattering Physics Proteins Soft Condensed Matter Spectra
Online-Zugang:	Volltext
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