Impact of Interleukin-6 on Drug-Metabolizing Enzymes and Transporters in Intestinal Cells

Inflammatory response is characterized by an increase of several cytokines. Some are known to modify drugs pharmacokinetic by reducing the expression levels of drug-metabolizing enzymes (DMEs) and transporters. This impact of inflammatory signaling is well established in hepatic cells, but not in in...

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Veröffentlicht in:	The AAPS journal 2019-12, Vol.22 (1), p.16, Article 16
Hauptverfasser:	Simon, Florian, Garcia, Jessica, Guyot, Laetitia, Guitton, Jérôme, Vilchez, Gaelle, Bardel, Claire, Chenel, Marylore, Tod, Michel, Payen, Léa
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biomedical and Life Sciences Biomedicine Biotechnology Pharmacology/Toxicology Pharmacy Research Article Statistics
Online-Zugang:	Volltext
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