Characterization of 164 patients with NRAS mutated non-small cell lung cancer (NSCLC)

•NRAS mutated NSCLC are mostly found in men with smoking history.•NRAS mutated NSCLC are characterized by a high frequency of codon 61 mutations.•Efficacy of immunotherapy combined with chemotherapy needs further investigation.•NRAS codon 61 mutation should be considered in targeted therapy developm...

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Veröffentlicht in:	Lung cancer (Amsterdam, Netherlands) Netherlands), 2023-12, Vol.186, p.107393-107393, Article 107393
Hauptverfasser:	Dehem, Agathe, Mazieres, Julien, Chour, Ali, Guisier, Florian, Ferreira, Marion, Boussageon, Maxime, Girard, Nicolas, Moro-Sibilot, Denis, Cadranel, Jacques, Zalcman, Gérard, Ricordel, Charles, Wislez, Marie, Munck, Camille, Poulet, Claire, Gauvain, Clément, Descarpentries, Clotilde, Wasielewski, Eric, Cortot, Alexis B., Baldacci, Simon
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemotherapy Immune checkpoint inhibitors Life Sciences Non-small cell lung cancer (NSCLC) NRAS Targeted therapies
Online-Zugang:	Volltext
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