Discovery of a non-canonical prototype long-chain monoacylglycerol lipase through a structure-based endogenous reaction intermediate complex

ABSTRACT The identification and characterization of enzyme function is largely lacking behind the rapidly increasing availability of large numbers of sequences and associated high-resolution structures. This is often hampered by lack of knowledge on in vivo relevant substrates. Here, we present a ca...

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Veröffentlicht in:	Nature communications 2023-11, Vol.14 (1)
Hauptverfasser:	Pinotsis, Nikos, Krüger, Anna, Tomas, Nicolas, Chatziefthymiou, Spyros, Litz, Claudia, Mortensen, Simon Arnold, Daffé, Mamadou, Marrakchi, Hedia, Antranikian, Garabed, Wilmanns, Matthias
Format:	Artikel
Sprache:	eng
Schlagworte:	Life Sciences
Online-Zugang:	Volltext
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