Outbreak of an Uncommon Rifampin-resistant blaNDM-1Citrobacter amalonaticus Strain in a Digestive Rehabilitation Center: The Putative Role of Rifaximin

Outbreak of an Uncommon Rifampin-resistant blaNDM-1Citrobacter amalonaticus Strain in a Digestive Rehabilitation Center: The Putative Role of Rifaximin

Abstract We describe a sudden 2-week outbreak due to a blaNDM-1Citrobacter amalonaticus strain in a 22-bed digestive rehabilitation center. Three of the 5 colonized patients received long-term rifaximin treatment to prevent hepatic encephalopathy. The strains were genotypically identical, phenotypic...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Clinical infectious diseases 2020-08, Vol.71 (5), p.1331-1333
Hauptverfasser: Royer, Guilhem, Fourreau, Fréderic, Gomart, Camille, Maurand, Audrey, Hacquin, Bruno, Ducellier, David, Cizeau, Florence, Lo, Stéphane, Cordonnier-Jourdin, Catherine, Mercier-Darty, Mélanie, Decousser, Jean-Winoc
Format: Artikel
Sprache:eng
Schlagworte:
Anti-Bacterial Agents - pharmacology
Anti-Bacterial Agents - therapeutic use
Disease Outbreaks
Humans
Life Sciences
Microbial Sensitivity Tests
Rehabilitation Centers
Rifampin - pharmacology
Rifaximin
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Abstract We describe a sudden 2-week outbreak due to a blaNDM-1Citrobacter amalonaticus strain in a 22-bed digestive rehabilitation center. Three of the 5 colonized patients received long-term rifaximin treatment to prevent hepatic encephalopathy. The strains were genotypically identical, phenotypically resistant to rifampin, and harbored arr-3, a rifampin adenosine diphosphate-ribosyl transferase.
ISSN:1058-4838
1537-6591
DOI:10.1093/cid/ciz1172