Cerebral Phospho-Tau Acts Synergistically with Soluble Aβ42 Leading to Mild Cognitive Impairment in AAV-AD Rats

Background Alzheimer’s disease (AD) is a continuum of events beginning with an increase in brain soluble Aβ342 followed by the appearance of hyperphosphorylated tau (P-tau, asymptomatic stage). Mild Cognitive Impairment (MCI) then appears (prodromal stage). However, the individual contribution of th...

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Veröffentlicht in:	The Journal Of Prevention of Alzheimer's Disease 2022, Vol.9 (3), p.480-490
Hauptverfasser:	Souchet, B., Audrain, M., Gu, Y., Lindberg, M. F., Orefice, N. S., Rey, E., Cartier, N., Janel, N., Meijer, L., Braudeau, Jérôme
Format:	Artikel
Sprache:	eng
Schlagworte:	Geriatrics/Gerontology Life Sciences Medicine Medicine & Public Health Neurology Original Research
Online-Zugang:	Volltext
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