Nickel-Catalyzed Electro-Reductive Cross-Coupling of Aliphatic N‑Acyl Imides with Alkyl Halides as a Strategy for Dialkyl Ketone Synthesis: Scope and Mechanistic Investigations

The development and in-depth study of a cross-electrophile coupling of alkyl N-acyl imides with alkyl halides relying on the combination of nickel catalysis and electrochemistry are described. This methodology takes advantages of the stability and simple access of N-acyl imides as coupling partners...

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Veröffentlicht in:ACS catalysis 2022-10, Vol.12 (19), p.12315-12325
Hauptverfasser: Kerackian, Taline, Bouyssi, Didier, Pilet, Guillaume, Médebielle, Maurice, Monteiro, Nuno, Vantourout, Julien C., Amgoune, Abderrahmane
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Sprache:eng
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