Conformational dynamics of individual antibodies using computational docking and AFM

Molecular recognition between a receptor and a ligand requires a certain level of flexibility in macromolecules. In this study, we aimed at analyzing the conformational variability of receptors portrayed by monoclonal antibodies that have been individually imaged using atomic force microscopy (AFM)....

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Veröffentlicht in:Journal of molecular recognition 2013-11, Vol.26 (11), p.596-604
Hauptverfasser: Chaves, Rui C., Teulon, Jean-Marie, Odorico, Michael, Parot, Pierre, Chen, Shu-wen W., Pellequer, Jean-Luc
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Sprache:eng
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