A Composite Element Binding the Vitamin D Receptor and the Retinoic X Receptor α Mediates the Transforming Growth Factor-β Inhibition of Decorin Gene Expression in Articular Chondrocytes

Decorin, a small leucine-rich proteoglycan may play an important role in the attempt of cartilage repair initiated by chondrocytes in early stages of osteoarthritis, through its ability to bind collagen fibrils and growth factors such as transforming growth factor-β (TGF-β). We previously demonstrat...

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