Intergenerational effects on fertility in male and female mice after chronic exposure to environmental doses of NSAIDs and 17α-ethinylestradiol mixtures

Non-steroidal anti-inflammatory drugs (NSAIDs) and 17α-ethinylestradiol (EE2) are extensively used in human and veterinary medicine. Due to their partial removal by wastewater treatment plants, they are frequent environmental contaminants, particularly in drinking water. Here, we investigated the ad...

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Veröffentlicht in:	Food and chemical toxicology 2023-12, Vol.182, p.114085-114085, Article 114085
Hauptverfasser:	Philibert, Pascal, Stévant, Isabelle, Déjardin, Stéphanie, Girard, Mélissa, Sellem, Eli, Durix, Quentin, Messager, Aurélie, Gonzalez, Anne-Alicia, Mialhe, Xavier, Pruvost, Alain, Poulat, Francis, Boizet-Bonhoure, Brigitte
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents, Non-Steroidal - toxicity Drinking Water Ecotoxicology EE2 Environmental doses Ethinyl Estradiol - toxicity Fertility Gonad transcriptome Humans Ibuprofen - pharmacology Life Sciences Male Mice NSAIDs Ovary Reproduction Reproductive Biology Semen Sexual reproduction Testis Toxicology Water Pollutants, Chemical - toxicity
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