Sex-related exacerbation of injury-induced mechanical hypersensitivity in GAD67 haplodeficient mice

Decreased GABA levels in injury-induced loss of spinal inhibition are still under intense interest and debate. Here, we show that GAD67 haplodeficient mice exhibited a prolonged injury-induced mechanical hypersensitivity in postoperative, inflammatory, and neuropathic pain models. In line with this,...

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Veröffentlicht in:Pain (Amsterdam) 2024-01, Vol.165 (1), p.192-201
Hauptverfasser: Charron, Aude, Pepino, Lucie, Malapert, Pascale, Debrauwer, Vincent, Castets, Francis, Salio, Chiara, Moqrich, Aziz
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Sprache:eng
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