Toxicological effects of 2,3,7,8 tetrachlorodibenzo-p-dioxin on the skeletal muscle of mice during the perinatal period: a metabolomics study

Persistent organic pollutants (POPs) accumulate in the organisms due to their hydrophobicity and resistance to xenobiotic metabolism. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is one of most representative POPs. Its pathophysiological effects have been extensively studied on many types of tissues b...

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Veröffentlicht in:	Environmental sciences Europe 2022-12, Vol.34 (1), p.57-57, Article 57
Hauptverfasser:	Lam, Gideon, Juricek, Ludmila, Dayal, Hiranya, Laserna, Anna Karen Carrasco, Hichor, Medhi, Blanc, Etienne, Chauvet, Caroline, Noirez, Phillipe, Coumoul, Xavier, Li, Sam Fong Yau
Format:	Artikel
Sprache:	eng
Schlagworte:	adulthood adults Age amino acid metabolism Amino acids Atrophy Bioaccumulation corn oil Dioxins Earth and Environmental Science Ecotoxicology Environment Environmental Sciences Europe Exposure Females Gas chromatography Hydrophobicity Lactation Long-term effects Mass spectrometry Mass spectroscopy maternal exposure Metabolism Metabolites Metabolomics mice Multivariate analysis Muscles muscular atrophy Musculoskeletal system Oils & fats Perinatal exposure perinatal period Persistent organic pollutants Pollutants Pollution pregnancy Progeny Quadrupoles Skeletal muscle TCDD tetrachlorodibenzo-p-dioxin xenobiotics
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