p53 functional loss, stemness and hepatocellular carcinoma

The tumor suppressor p53 is a key player in the control of genomic integrity and homeostasis in connection with p63 and p73, the two other members of the p53 family. Loss of functional p53 leads to the proliferation and survival of mature cells and progenitor or stem cells that accumulate genetic al...

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Veröffentlicht in:	Hepatoma research 2020, Vol.2020
Hauptverfasser:	De Fromentel, Claude Caron, Levrero, Massimo
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry, Molecular Biology Cancer Genomics Human health and pathology Hépatology and Gastroenterology Life Sciences
Online-Zugang:	Volltext
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