In Vitro and Ex Vivo Models for Assessing Drug Permeation across the Cornea

Drug permeation across the cornea remains a major challenge due to its unique and complex anatomy and physiology. Static barriers such as the different layers of the cornea, as well as dynamic aspects such as the constant renewal of the tear film and the presence of the mucin layer together with eff...

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Veröffentlicht in:	Molecular pharmaceutics 2023-07, Vol.20 (7), p.3298-3319
Hauptverfasser:	De Hoon, Inès, Boukherroub, Rabah, De Smedt, Stefaan C., Szunerits, Sabine, Sauvage, Félix
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Ophthalmic Animals Cell Culture Techniques Cornea Engineering Sciences Permeability Pharmaceutical Preparations Physics Swine
Online-Zugang:	Volltext
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