Long‐term safety and efficacy of rituximab in 248 adults with immune thrombocytopenia: Results at 5 years from the French prospective registry ITP‐ritux

Rituximab is a second‐line option in adults with immune thrombocytopenia (ITP), but the estimated 5‐year response rate, only based on pooled retrospective data, is about 20%, and no studies have focused on long‐term safety. We conducted a prospective multicenter registry of 248 adults with ITP treat...

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Veröffentlicht in:	American journal of hematology 2019-12, Vol.94 (12), p.1314-1324
Hauptverfasser:	Deshayes, Samuel, Khellaf, Mehdi, Zarour, Anissa, Layese, Richard, Fain, Olivier, Terriou, Louis, Viallard, Jean‐François, Cheze, Stéphane, Graveleau, Julie, Slama, Borhane, Audia, Sylvain, Cliquennois, Manuel, Ebbo, Mikael, Le Guenno, Guillaume, Salles, Gilles, Bonmati, Caroline, Teillet, France, Galicier, Lionel, Lambotte, Olivier, Hot, Arnaud, Lefrère, François, Mahévas, Matthieu, Canoui‐Poitrine, Florence, Michel, Marc, Godeau, Bertrand
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Cortex Hormones - therapeutic use Adult Agammaglobulinemia - chemically induced Agammaglobulinemia - epidemiology Aged Aged, 80 and over Autoimmune Diseases - epidemiology Autoimmune Diseases - etiology Cardiovascular Diseases - epidemiology Cardiovascular Diseases - etiology Cause of Death Disease-Free Survival Drug Eruptions - epidemiology Drug Eruptions - etiology Drug Substitution Female Follow-Up Studies France - epidemiology Hematology Human health and pathology Humans Infections - epidemiology Life Sciences Male Middle Aged Neoplasms - epidemiology Neoplasms - etiology Neoplasms - immunology Pharmaceutical sciences Pharmacology Pregnancy Pregnancy Complications - epidemiology Pregnancy Outcome Prospective Studies Purpura, Thrombocytopenic, Idiopathic - drug therapy Purpura, Thrombocytopenic, Idiopathic - mortality Registries Rituximab - adverse effects Rituximab - therapeutic use Santé publique et épidémiologie Serum Sickness - chemically induced Serum Sickness - epidemiology
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