Transinteractome analysis reveals distinct niche requirements for isotype-based plasma cell subsets in the bone marrow

Bone marrow (BM) long-lived plasma cells (PCs) are essential for long-term protection against infection, and their persistence within this organ relies on interactions with Cxcl12-expressing stromal cells that are still not clearly identified. Here, using single cell RNAseq and in silico transintera...

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Veröffentlicht in:	European journal of immunology 2023-09, Vol.53 (9), p.e2250334-e2250334
Hauptverfasser:	Bonaud, Amélie, Larraufie, Pierre, Khamyath, Mélanie, Szachnowski, Ugo, Flint, Shaun M, Brunel-Meunier, Nadège, Delhommeau, François, Munier, Annie, Lönnberg, Tapio, Toffano-Nioche, Claire, Gautheret, Daniel, Balabanian, Karl, Espéli, Marion
Format:	Artikel
Sprache:	eng
Schlagworte:	Bone marrow Cell adhesion molecules CXCL12 protein Integrins Life Sciences Long bone Mesenchyme Plasma cell Bone marrow Niche Stromal cell Transinteractome Plasma cells Stromal cells
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