Alternative routes for tranexamic acid treatment in obstetric bleeding (WOMAN‐PharmacoTXA trial): a randomised trial and pharmacological study in caesarean section births

Objective To examine the safety, efficacy and pharmacology of intravenous (IV), intramuscular (IM) and oral tranexamic acid (TXA) use in pregnant women. Design Randomised, open‐label trial. Setting Hospitals in Pakistan and Zambia. Population Women giving birth by caesarean section. Methods Women we...

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Veröffentlicht in:	BJOG : an international journal of obstetrics and gynaecology 2023-09, Vol.130 (10), p.1177-1186
Hauptverfasser:	Shakur‐Still, Haleema, Roberts, Ian, Grassin‐Delyle, Stanislas, Chaudhri, Rizwana, Geer, Amber, Arribas, Monica, Lamy, Elodie, Mansukhani, Raoul, Lubeya, Mwansa Ketty, Javaid, Kiran, Kayani, Aasia, Israr, Naila, Mazhar, Syeda Batool, Urien, Saïk, Bouazza, Naïm, Foissac, Frantz, Prowse, Danielle, Carrington, Laura, Barrow, Collette, Onandia, Julio Gil, Balogun, Eni
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intravenous Adverse events Antifibrinolytic agents Antifibrinolytic Agents - therapeutic use Blood levels caesarean section Cesarean Section clinical trial Cord blood Female Fibrinolysis Gynecology and obstetrics Hemorrhage Human health and pathology Humans Infant, Newborn intramuscular Life Sciences Neonates oral Oral administration Parturition pharmacodynamics Pharmacokinetics postpartum haemorrhage Pregnancy tranexamic acid Tranexamic Acid - therapeutic use
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