Transplacental delivery of therapeutic proteins by engineered IgG: a step towards perinatal replacement therapy

Background: Transplacental delivery of maternal IgG provides humoral protection during the first months of life until the newborn’s immune system reaches maturity. The materno-fetal interface has been exploited therapeutically to replace missing enzymes in the fetus, as shown in experimental mucopol...

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Veröffentlicht in:Journal of thrombosis and haemostasis 2023-06
Hauptverfasser: Mimoun, Angelina, Bou Jaoudeh, Melissa, Delignat, Sandrine, Daventure, Victoria, Reyes Ruiz, Alejandra, Lecerf, Maxime, Azam, Aurélien, Noe, Remi, Peyron, Ivan, Christophe, Olivier, Lenting, Peter, Proulle, Valérie, Mcintosh, Jenny, Nathwani, Amit, Dimitrov, Jordan, Denis, Cécile, Lacroix-Desmazes, Sébastien
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Sprache:eng
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