Spatial transcriptomics reveal pitfalls and opportunities for the detection of rare high-plasticity breast cancer subtypes

Breast cancer is one of the most prominent types of cancers, in which therapeutic resistance is still a major clinical hurdle. Specific subtypes like Claudin-low (CL) and metaplastic breast cancers (MpBC) have been associated with high non-genetic plasticity, which can facilitate resistance. The ove...

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Veröffentlicht in:Laboratory investigation 2023-04
Hauptverfasser: Coutant, Angèle, Cockenpot, Vincent, Muller, Lauriane, Degletagne, Cyril, Pommier, Roxane, Tonon, Laurie, Ardin, Maude, Michallet, Marie-Cécile, Caux, Christophe, Laurent, Marie, Morel, Anne-Pierre, Saintigny, Pierre, Puisieux, Alain, Ouzounova, Maria, Martinez, Pierre
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Sprache:eng
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