Comparison of c-13 mri of hyperpolarized [1-c-13]pyruvate and lactate with the corresponding mass spectrometry images in a murine lymphoma model

PURPOSE: To compare carbon-13 ((13) C) MRSI of hyperpolarized [1-(13) C]pyruvate metabolism in a murine tumor model with mass spectrometric (MS) imaging of the corresponding tumor sections in order to cross validate these metabolic imaging techniques and to investigate the effects of pyruvate delive...

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Veröffentlicht in:Magnetic resonance in medicine 2021-06, Vol.85 (6), p.3027-3035
Hauptverfasser: Fala, Maria, Somai, Vencel, Dannhorn, Andreas, Hamm, Gregory, Gibson, Katherine, Couturier, Dominique-Laurent, Hesketh, Richard, Wright, Alan J., Takats, Zoltan, Bunch, Josephine, Barry, Simon T., Goodwin, Richard J. A., Brindle, Kevin M.
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Sprache:eng
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