Identification of the N-glycosylation sites on recombinant bovine CD38 expressed in Pichia pastoris: Their impact on enzyme stability and catalytic activity

Bovine CD38, a type II glycoprotein, contains two potential N-glycosylation sites (Asn-201 and Asn-268) in its extracellular domain. This contrasts with the other mammalian members of the ADP-ribosyl cyclase family, such as human CD38 and BST-1/CD157, in which four such sites are present. Our study...

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Veröffentlicht in:Protein expression and purification 2010-04, Vol.70 (2), p.151-157
Hauptverfasser: Muller-Steffner, Hélène, Kuhn, Isabelle, Argentini, Manuela, Schuber, Francis
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Sprache:eng
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