A novel myeloid-like NK cell progenitor in human umbilical cord blood

Natural killer (NK) cell differentiation from pluripotent CD34+ human hematopoietic stem cells or oligopotent lymphoid progenitors has already been reported. In the present study, long-term cultures of the CD56−/CD34−myeloid-like adherent cell fraction (ACF) from umbilical cord blood (UCB), characte...

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Veröffentlicht in:	Blood 2003-05, Vol.101 (9), p.3444-3450
Hauptverfasser:	Perez, Sonia A., Sotiropoulou, Panagiota A., Gkika, Dimitra G., Mahaira, Louisa G., Niarchos, Dimitrios K., Gritzapis, Angelos D., Kavalakis, Yiannis G., Antsaklis, Aris I., Baxevanis, Constantin N., Papamichail, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Burkitt Lymphoma - pathology CD56 Antigen - biosynthesis Cell Differentiation - drug effects Cell differentiation, maturation, development, hematopoiesis Cell physiology Cells, Cultured - cytology Cells, Cultured - metabolism Cytotoxicity, Immunologic Fetal Blood - cytology Fundamental and applied biological sciences. Psychology Granulocyte-Macrophage Colony-Stimulating Factor - biosynthesis Hematopoietic Stem Cells - cytology Hematopoietic Stem Cells - drug effects Humans Immunophenotyping Infant, Newborn Interferon-gamma - biosynthesis Interleukin-10 - biosynthesis Interleukin-15 - pharmacology K562 Cells Killer Cells, Natural - cytology Life Sciences Lipopolysaccharide Receptors - biosynthesis Membrane Proteins - pharmacology Mice Molecular and cellular biology Multiple Myeloma - pathology Myeloid Cells - classification Tumor Cells, Cultured Tumor Necrosis Factor-alpha - biosynthesis
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