Targeting nonsense-mediated mRNA decay in colorectal cancers with microsatellite instability

Abstract Nonsense-mediated mRNA decay (NMD) is responsible for the degradation of mRNAs with a premature termination codon (PTC). The role of this system in cancer is still quite poorly understood. In the present study, we evaluated the functional consequences of NMD activity in a subgroup of colore...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Oncogenesis (New York, NY) NY), 2018-09, Vol.7 (9)
Hauptverfasser:	Bokhari, A’dem, Jonchere, Vincent, Lagrange, Anaïs, Bertrand, Romane, Svrcek, Magali, Marisa, Laetitia, Buhard, Olivier, Greene, Malorie, Demidova, Anastasia, Jia, Jieshuang, Adriaenssens, Eric, Chassat, Thierry, Biard, Denis S, Flejou, Jean-François, Lejeune, Fabrice, Duval, Alex, Collura, Ada
Format:	Artikel
Sprache:	eng
Schlagworte:	Life Sciences
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!