UHRF1 regulates CDH1 via promoter associated non-coding RNAs in prostate cancer cells

Non-coding RNAs (ncRNAs) transcribed from the promoter and the downstream region can affect the expression of the corresponding coding genes. It has been shown that sense-directed ncRNAs arising from the promoter region of the E-cadherin gene (CDH1) mediate its repression. Here, we show that an anti...

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Veröffentlicht in:	Biochimica et biophysica acta. Gene regulatory mechanisms 2018-03, Vol.1861 (3), p.258-270
Hauptverfasser:	Magnani, Elena, Macchi, Filippo, Mancini, Monica, Lomazzi, Vanessa, Cogliati, Sara, Pistore, Christian, Mandruzzato, Martina, Dock-Bregeon, Anne-Catherine, Bonapace, Ian Marc
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD Bidirectional promoters Cadherins - genetics Cadherins - metabolism CCAAT-Enhancer-Binding Proteins - metabolism CDH1 Cell Line, Tumor Epigenesis, Genetic Gene Expression Regulation, Neoplastic Gene Silencing Humans Life Sciences Male Models, Biological Promoter Regions, Genetic Promoter-associated non-coding RNAs Prostatic Neoplasms - genetics Protein Binding - genetics RNA, Messenger - genetics RNA, Messenger - metabolism RNA, Untranslated - genetics RNA, Untranslated - metabolism UHRF1
Online-Zugang:	Volltext
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