Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis

During endocytosis, clathrin and the clathrin adaptor protein AP-2 ( ref. 1 ), assisted by a variety of accessory factors, help to generate an invaginated bud at the cell membrane 2 , 3 . One of these factors is Eps15, a clathrin-coat-associated protein that binds the α-adaptin subunit of AP-2 ( 4 –...

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