Effect of pravastatin on erythrocyte rheological and biochemical properties in poorly controlled Type 2 diabetic patients

Summary Aims The rheological properties of erythrocytes are impaired in diabetes mellitus, especially because of changes in their membrane lipid composition. In hypercholesterolaemic patients, lowering plasma cholesterol is associated with an improvement of the erythrocyte rheological parameters. Th...

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Veröffentlicht in:	Diabetic medicine 1999-05, Vol.16 (5), p.424-430
Hauptverfasser:	Miossec, P., Zkhiri, F., Pariès, J., David‐Dufilho, M., Devynck, M. A., Valensi, P. E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticholesteremic Agents - therapeutic use Biological and medical sciences Blood Pressure - drug effects blood rheology Cholesterol - blood Cholesterol, HDL - blood Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - complications Double-Blind Method Electrolytes - blood Erythrocyte Deformability - drug effects Erythrocyte Deformability - physiology Erythrocyte Membrane - drug effects Erythrocyte Membrane - physiology erythrocytes Erythrocytes - drug effects Erythrocytes - metabolism Erythrocytes - physiology Female Fructosamine - blood General and cellular metabolism. Vitamins Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Hypercholesterolemia - blood Hypercholesterolemia - drug therapy Life Sciences lipid lowering agent Male Medical sciences Middle Aged Pharmacology. Drug treatments Phospholipids - blood Placebos Pravastatin - therapeutic use Reference Values Rheology statin Type 2 diabetes mellitus
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