Group IIA secreted phospholipase A2 (PLA2G2A) augments adipose tissue thermogenesis

Group IIA secreted phospholipase A2 (PLA2G2A) hydrolyzes glycerophospholipids at the sn‐2 position resulting in the release of fatty acids and lysophospholipids. C57BL/6 mice do not express Pla2g2a due to a frameshift mutation (wild‐type [WT] mice). We previously reported that transgenic expression...

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Veröffentlicht in:	The FASEB journal 2021-10, Vol.35 (10), p.e21881-n/a
Hauptverfasser:	Kuefner, Michael S., Stephenson, Erin, Savikj, Mladen, Smallwood, Heather S., Dong, Qingming, Payré, Christine, Lambeau, Gérard, Park, Edwards A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue, Brown - physiopathology Adipose Tissue, White - physiopathology Animals Biological Transport brown adipose tissue Energy Metabolism Female Group II Phospholipases A2 - physiology Life Sciences Male Mice Mice, Inbred C57BL Mice, Knockout Mitochondria - metabolism Mitochondria - pathology PLA2G2A Thermogenesis UCP1 Uncoupling Protein 1 - metabolism
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