Dermatomyositis: new antibody, new classification
Dermatomyositis are rare chronic auto-immune diseases characterized by cutaneous involvement. Diagnosis could be made in childhood or in aldult. There are some different clinical and histological presentation associated with different myositis specific antibody. There are five dermatomyositis specif...
Gespeichert in:
| Veröffentlicht in: | M.S. Médecine sciences 2019-11, Vol.35 Hors série n° 2, p.18-23 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | fre |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 23 |
|---|---|
| container_issue | |
| container_start_page | 18 |
| container_title | M.S. Médecine sciences |
| container_volume | 35 Hors série n° 2 |
| creator | Bolko, Loïs Gitiaux, Cyril Allenbach, Yves |
| description | Dermatomyositis are rare chronic auto-immune diseases characterized by cutaneous involvement. Diagnosis could be made in childhood or in aldult. There are some different clinical and histological presentation associated with different myositis specific antibody. There are five dermatomyositis specific autoantibodies, anti-Mi2, anti-Tif1-γ, anti-NXP2, anti-MDA5, and anti-SAE. Anti-Mi2 are associated with "classical form" of DM with cutaneous and muscular involvement. Anti-Tif1γ and anti-NXP2 are found in juvenile and adult dermatomyositis, and are associated with recurrent diseases with cutaneous involvement at the forefront. In adults, they are associated with cancer. Anti-MDA5 antibodies are associated with a systemic involvement and an interstitial lung disease. Finally, anti-SAE have been found only in adults, with a classic form. |
| doi_str_mv | 10.1051/medsci/2019178 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_hal_p</sourceid><recordid>TN_cdi_hal_primary_oai_HAL_hal_03832528v1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2329728907</sourcerecordid><originalsourceid>FETCH-LOGICAL-h175t-1858d184674567c9305c7547ab0ce1b896b6138172a345fb90b9fa96898763213</originalsourceid><addsrcrecordid>eNo9kM1LAzEUxIMotlavHqVHBdfmJZu8xFupHxUKXvS8JGmWRnY3dbNV-t-7tdXTYx4_ZoYh5BLoHVABk9ovkwsTRkEDqiMyBC1UJriCYzKkKDGjGvMBOUvpg1IGgvFTMuCghJZMDgk8-LY2Xay3MYUupPtx47_HpumCjcvt7a9ylUkplMGZLsTmnJyUpkr-4nBH5P3p8W02zxavzy-z6SJbAYou6xPUElQuMRcSneZUOBQ5GkudB6u0tBL6msgMz0VpNbW6NFoqrVByBnxEbva-K1MV6zbUpt0W0YRiPl0Uux_lijPB1NeOvd6z6zZ-bnzqijok56vKND5uUsE408iUptijVwd0Y_vx_p3_JuE_KkRgag</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2329728907</pqid></control><display><type>article</type><title>Dermatomyositis: new antibody, new classification</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Bolko, Loïs ; Gitiaux, Cyril ; Allenbach, Yves</creator><creatorcontrib>Bolko, Loïs ; Gitiaux, Cyril ; Allenbach, Yves</creatorcontrib><description>Dermatomyositis are rare chronic auto-immune diseases characterized by cutaneous involvement. Diagnosis could be made in childhood or in aldult. There are some different clinical and histological presentation associated with different myositis specific antibody. There are five dermatomyositis specific autoantibodies, anti-Mi2, anti-Tif1-γ, anti-NXP2, anti-MDA5, and anti-SAE. Anti-Mi2 are associated with "classical form" of DM with cutaneous and muscular involvement. Anti-Tif1γ and anti-NXP2 are found in juvenile and adult dermatomyositis, and are associated with recurrent diseases with cutaneous involvement at the forefront. In adults, they are associated with cancer. Anti-MDA5 antibodies are associated with a systemic involvement and an interstitial lung disease. Finally, anti-SAE have been found only in adults, with a classic form.</description><identifier>ISSN: 0767-0974</identifier><identifier>EISSN: 1958-5381</identifier><identifier>DOI: 10.1051/medsci/2019178</identifier><identifier>PMID: 31859626</identifier><language>fre</language><publisher>France: EDP Sciences</publisher><subject>Adenosine Triphosphatases ; Adenosine Triphosphatases - immunology ; Adult ; Age of Onset ; Autoantibodies ; Autoantibodies - blood ; Autoantibodies - isolation & purification ; Child ; Dermatomyositis ; Dermatomyositis - blood ; Dermatomyositis - classification ; Dermatomyositis - diagnosis ; Dermatomyositis - epidemiology ; DNA-Binding Proteins ; DNA-Binding Proteins - immunology ; Humans ; Interferon-Induced Helicase, IFIH1 ; Interferon-Induced Helicase, IFIH1 - immunology ; Life Sciences ; Lung Diseases, Interstitial ; Lung Diseases, Interstitial - blood ; Lung Diseases, Interstitial - diagnosis ; Lung Diseases, Interstitial - etiology ; Mi-2 Nucleosome Remodeling and Deacetylase Complex ; Mi-2 Nucleosome Remodeling and Deacetylase Complex - immunology ; Terminology as Topic ; Transcription Factors ; Transcription Factors - immunology ; Ubiquitin-Activating Enzymes ; Ubiquitin-Activating Enzymes - immunology</subject><ispartof>M.S. Médecine sciences, 2019-11, Vol.35 Hors série n° 2, p.18-23</ispartof><rights>2019 médecine/sciences – Inserm.</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><orcidid>0000-0002-2190-6843 ; 0000-0002-3185-7993</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31859626$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-03832528$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Bolko, Loïs</creatorcontrib><creatorcontrib>Gitiaux, Cyril</creatorcontrib><creatorcontrib>Allenbach, Yves</creatorcontrib><title>Dermatomyositis: new antibody, new classification</title><title>M.S. Médecine sciences</title><addtitle>Med Sci (Paris)</addtitle><description>Dermatomyositis are rare chronic auto-immune diseases characterized by cutaneous involvement. Diagnosis could be made in childhood or in aldult. There are some different clinical and histological presentation associated with different myositis specific antibody. There are five dermatomyositis specific autoantibodies, anti-Mi2, anti-Tif1-γ, anti-NXP2, anti-MDA5, and anti-SAE. Anti-Mi2 are associated with "classical form" of DM with cutaneous and muscular involvement. Anti-Tif1γ and anti-NXP2 are found in juvenile and adult dermatomyositis, and are associated with recurrent diseases with cutaneous involvement at the forefront. In adults, they are associated with cancer. Anti-MDA5 antibodies are associated with a systemic involvement and an interstitial lung disease. Finally, anti-SAE have been found only in adults, with a classic form.</description><subject>Adenosine Triphosphatases</subject><subject>Adenosine Triphosphatases - immunology</subject><subject>Adult</subject><subject>Age of Onset</subject><subject>Autoantibodies</subject><subject>Autoantibodies - blood</subject><subject>Autoantibodies - isolation & purification</subject><subject>Child</subject><subject>Dermatomyositis</subject><subject>Dermatomyositis - blood</subject><subject>Dermatomyositis - classification</subject><subject>Dermatomyositis - diagnosis</subject><subject>Dermatomyositis - epidemiology</subject><subject>DNA-Binding Proteins</subject><subject>DNA-Binding Proteins - immunology</subject><subject>Humans</subject><subject>Interferon-Induced Helicase, IFIH1</subject><subject>Interferon-Induced Helicase, IFIH1 - immunology</subject><subject>Life Sciences</subject><subject>Lung Diseases, Interstitial</subject><subject>Lung Diseases, Interstitial - blood</subject><subject>Lung Diseases, Interstitial - diagnosis</subject><subject>Lung Diseases, Interstitial - etiology</subject><subject>Mi-2 Nucleosome Remodeling and Deacetylase Complex</subject><subject>Mi-2 Nucleosome Remodeling and Deacetylase Complex - immunology</subject><subject>Terminology as Topic</subject><subject>Transcription Factors</subject><subject>Transcription Factors - immunology</subject><subject>Ubiquitin-Activating Enzymes</subject><subject>Ubiquitin-Activating Enzymes - immunology</subject><issn>0767-0974</issn><issn>1958-5381</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kM1LAzEUxIMotlavHqVHBdfmJZu8xFupHxUKXvS8JGmWRnY3dbNV-t-7tdXTYx4_ZoYh5BLoHVABk9ovkwsTRkEDqiMyBC1UJriCYzKkKDGjGvMBOUvpg1IGgvFTMuCghJZMDgk8-LY2Xay3MYUupPtx47_HpumCjcvt7a9ylUkplMGZLsTmnJyUpkr-4nBH5P3p8W02zxavzy-z6SJbAYou6xPUElQuMRcSneZUOBQ5GkudB6u0tBL6msgMz0VpNbW6NFoqrVByBnxEbva-K1MV6zbUpt0W0YRiPl0Uux_lijPB1NeOvd6z6zZ-bnzqijok56vKND5uUsE408iUptijVwd0Y_vx_p3_JuE_KkRgag</recordid><startdate>201911</startdate><enddate>201911</enddate><creator>Bolko, Loïs</creator><creator>Gitiaux, Cyril</creator><creator>Allenbach, Yves</creator><general>EDP Sciences</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>1XC</scope><orcidid>https://orcid.org/0000-0002-2190-6843</orcidid><orcidid>https://orcid.org/0000-0002-3185-7993</orcidid></search><sort><creationdate>201911</creationdate><title>Dermatomyositis: new antibody, new classification</title><author>Bolko, Loïs ; Gitiaux, Cyril ; Allenbach, Yves</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-h175t-1858d184674567c9305c7547ab0ce1b896b6138172a345fb90b9fa96898763213</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>fre</language><creationdate>2019</creationdate><topic>Adenosine Triphosphatases</topic><topic>Adenosine Triphosphatases - immunology</topic><topic>Adult</topic><topic>Age of Onset</topic><topic>Autoantibodies</topic><topic>Autoantibodies - blood</topic><topic>Autoantibodies - isolation & purification</topic><topic>Child</topic><topic>Dermatomyositis</topic><topic>Dermatomyositis - blood</topic><topic>Dermatomyositis - classification</topic><topic>Dermatomyositis - diagnosis</topic><topic>Dermatomyositis - epidemiology</topic><topic>DNA-Binding Proteins</topic><topic>DNA-Binding Proteins - immunology</topic><topic>Humans</topic><topic>Interferon-Induced Helicase, IFIH1</topic><topic>Interferon-Induced Helicase, IFIH1 - immunology</topic><topic>Life Sciences</topic><topic>Lung Diseases, Interstitial</topic><topic>Lung Diseases, Interstitial - blood</topic><topic>Lung Diseases, Interstitial - diagnosis</topic><topic>Lung Diseases, Interstitial - etiology</topic><topic>Mi-2 Nucleosome Remodeling and Deacetylase Complex</topic><topic>Mi-2 Nucleosome Remodeling and Deacetylase Complex - immunology</topic><topic>Terminology as Topic</topic><topic>Transcription Factors</topic><topic>Transcription Factors - immunology</topic><topic>Ubiquitin-Activating Enzymes</topic><topic>Ubiquitin-Activating Enzymes - immunology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bolko, Loïs</creatorcontrib><creatorcontrib>Gitiaux, Cyril</creatorcontrib><creatorcontrib>Allenbach, Yves</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>M.S. Médecine sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bolko, Loïs</au><au>Gitiaux, Cyril</au><au>Allenbach, Yves</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dermatomyositis: new antibody, new classification</atitle><jtitle>M.S. Médecine sciences</jtitle><addtitle>Med Sci (Paris)</addtitle><date>2019-11</date><risdate>2019</risdate><volume>35 Hors série n° 2</volume><spage>18</spage><epage>23</epage><pages>18-23</pages><issn>0767-0974</issn><eissn>1958-5381</eissn><abstract>Dermatomyositis are rare chronic auto-immune diseases characterized by cutaneous involvement. Diagnosis could be made in childhood or in aldult. There are some different clinical and histological presentation associated with different myositis specific antibody. There are five dermatomyositis specific autoantibodies, anti-Mi2, anti-Tif1-γ, anti-NXP2, anti-MDA5, and anti-SAE. Anti-Mi2 are associated with "classical form" of DM with cutaneous and muscular involvement. Anti-Tif1γ and anti-NXP2 are found in juvenile and adult dermatomyositis, and are associated with recurrent diseases with cutaneous involvement at the forefront. In adults, they are associated with cancer. Anti-MDA5 antibodies are associated with a systemic involvement and an interstitial lung disease. Finally, anti-SAE have been found only in adults, with a classic form.</abstract><cop>France</cop><pub>EDP Sciences</pub><pmid>31859626</pmid><doi>10.1051/medsci/2019178</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0002-2190-6843</orcidid><orcidid>https://orcid.org/0000-0002-3185-7993</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0767-0974 |
| ispartof | M.S. Médecine sciences, 2019-11, Vol.35 Hors série n° 2, p.18-23 |
| issn | 0767-0974 1958-5381 |
| language | fre |
| recordid | cdi_hal_primary_oai_HAL_hal_03832528v1 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adenosine Triphosphatases Adenosine Triphosphatases - immunology Adult Age of Onset Autoantibodies Autoantibodies - blood Autoantibodies - isolation & purification Child Dermatomyositis Dermatomyositis - blood Dermatomyositis - classification Dermatomyositis - diagnosis Dermatomyositis - epidemiology DNA-Binding Proteins DNA-Binding Proteins - immunology Humans Interferon-Induced Helicase, IFIH1 Interferon-Induced Helicase, IFIH1 - immunology Life Sciences Lung Diseases, Interstitial Lung Diseases, Interstitial - blood Lung Diseases, Interstitial - diagnosis Lung Diseases, Interstitial - etiology Mi-2 Nucleosome Remodeling and Deacetylase Complex Mi-2 Nucleosome Remodeling and Deacetylase Complex - immunology Terminology as Topic Transcription Factors Transcription Factors - immunology Ubiquitin-Activating Enzymes Ubiquitin-Activating Enzymes - immunology |
| title | Dermatomyositis: new antibody, new classification |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T17%3A10%3A17IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_hal_p&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Dermatomyositis:%20new%20antibody,%20new%20classification&rft.jtitle=M.S.%20M%C3%A9decine%20sciences&rft.au=Bolko,%20Lo%C3%AFs&rft.date=2019-11&rft.volume=35%20Hors%20s%C3%A9rie%20n%C2%B0%202&rft.spage=18&rft.epage=23&rft.pages=18-23&rft.issn=0767-0974&rft.eissn=1958-5381&rft_id=info:doi/10.1051/medsci/2019178&rft_dat=%3Cproquest_hal_p%3E2329728907%3C/proquest_hal_p%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2329728907&rft_id=info:pmid/31859626&rfr_iscdi=true |