KIR3DL2 contributes to the typing of acute adult T-cell leukemia and is a potential therapeutic target

Adult T-cell leukemia (ATL) is a lymphoid neoplasm caused by human T-cell leukemia virus type 1 (HTLV-1), which encodes the transcriptional activator Tax, which participates in the immortalization of infected T cells. ATL is classified into 4 subtypes: smoldering, chronic, acute, and lymphoma. We de...

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Veröffentlicht in:	Blood 2022-09, Vol.140 (13), p.1522-1532
Hauptverfasser:	Cheminant, Morgane, Lhermitte, Ludovic, Bruneau, Julie, Sicard, Hélène, Bonnafous, Cécile, Touzart, Aurore, Bourbon, Estelle, Ortonne, Nicolas, Genestier, Laurent, Gaulard, Philippe, Palmic, Patricia, Suarez, Felipe, Frenzel, Laurent, Naveau, Louise, Bazarbachi, Ali, Dussiot, Mickaël, Waast, Laetitia, Avettand-Fenoel, Véronique, Brouzes, Chantal, Pique, Claudine, Lepelletier, Yves, Asnafi, Vahid, Marçais, Ambroise, Hermine, Olivier
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biochemistry, Molecular Biology Cancer Gene Products, tax - genetics Gene Products, tax - metabolism Genomics Hematology HTLV-I Infections - complications HTLV-I Infections - genetics Human health and pathology Human T-lymphotropic virus 1 - genetics Human T-lymphotropic virus 1 - metabolism Humans Infectious diseases Leukemia-Lymphoma, Adult T-Cell - pathology Life Sciences Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Receptors, KIR3DL2 - genetics RNA RNA, Messenger
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