Conception and Evaluation of Fluorescent Phosphine‐Gold Complexes: From Synthesis to in vivo Investigations

A phosphine gold(I) and phosphine‐phosphonium gold(I) complexes bearing a fluorescent coumarin moiety were synthesized and characterized. Both complexes displayed interesting photophysical properties: good molar absorption coefficient, good quantum yield of fluorescence, and ability to be tracked in...

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Veröffentlicht in:	ChemMedChem 2022-06, Vol.17 (11), p.e202100773-n/a
Hauptverfasser:	Rousselle, Benjamin, Massot, Aurélie, Privat, Malorie, Dondaine, Lucile, Trommenschlager, Audrey, Bouyer, Florence, Bayardon, Jérôme, Ghiringhelli, François, Bettaieb, Ali, Goze, Christine, Paul, Catherine, Malacea‐Kabbara, Raluca, Bodio, Ewen
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorptivity Animals Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Biological properties Cancer Chemical Sciences Coordination chemistry Coumarin Fluorescence Gold Gold - pharmacology gold complex In vivo methods and tests Medicinal Chemistry Mice Neoplasms Phosphine Phosphines Phosphines - pharmacology theranostic Tumor cell lines Tumors
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