Molecular mechanisms of transgenerational epigenetic inheritance

Increasing evidence indicates that non-DNA sequence-based epigenetic information can be inherited across several generations in organisms ranging from yeast to plants to humans. This raises the possibility of heritable ‘epimutations’ contributing to heritable phenotypic variation and thus to evoluti...

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Veröffentlicht in:	Nature reviews. Genetics 2022-06, Vol.23 (6), p.325-341
Hauptverfasser:	Fitz-James, Maximilian H., Cavalli, Giacomo
Format:	Artikel
Sprache:	eng
Schlagworte:	631/208/176 631/337/100 631/337/176 Agriculture Animal Genetics and Genomics Animals Biomedical and Life Sciences Biomedicine Cancer Research Databases, Genetic DNA Methylation Epigenesis, Genetic Epigenetics Epigenomics Gene Function Heredity Histones Human Genetics Inheritance Patterns Life Sciences Mammals Molecular modelling Nucleotide sequence Phenotypes Phenotypic variations Review Article Species
Online-Zugang:	Volltext
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