Percutaneous Cryoablation for Recurrent Head and Neck Tumors

Purpose To report techniques and results of 16 cryoablation procedures in 11 patients treated for recurrent head and neck cancer. Methods and Materials This retrospective study reviewed 11 consecutive patients with head and neck cancer recurrence after primary treatment by surgery and radiotherapy,...

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Veröffentlicht in:Cardiovascular and interventional radiology 2022-06, Vol.45 (6), p.791-799
Hauptverfasser: Schwartz, Jean, Auloge, Pierre, Koch, Guillaume, Robinson, Joey Marie, Garnon, Julien, Cazzato, Roberto Luigi, Perruisseau-Carrier, Joffrey, Debry, Christian, Gangi, Afshin
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container_end_page 799
container_issue 6
container_start_page 791
container_title Cardiovascular and interventional radiology
container_volume 45
creator Schwartz, Jean
Auloge, Pierre
Koch, Guillaume
Robinson, Joey Marie
Garnon, Julien
Cazzato, Roberto Luigi
Perruisseau-Carrier, Joffrey
Debry, Christian
Gangi, Afshin
description Purpose To report techniques and results of 16 cryoablation procedures in 11 patients treated for recurrent head and neck cancer. Methods and Materials This retrospective study reviewed 11 consecutive patients with head and neck cancer recurrence after primary treatment by surgery and radiotherapy, treated with cryoablation between 2016 and 2 020. Efficacy was measured by local control rate evaluated on MRI or/and PET. Tumor characteristics, number of cryoprobes, thermoprotective measures and complications were documented. Results Sixteen cryoablation procedures were performed in 11 patients with head and neck cancer recurrence after surgery or radiotherapy, deemed ineligible for classic salvage treatment. Among 11 patients, four were treated for an epidermoid carcinoma, four for an adenocarcinoma and three for other types: 1 muco-epidermoid carcinoma, 1 adenoid cystic carcinoma and 1 esthesioneuroblastoma, 10/11 patients had prior surgery, 7/11 patients had prior chemotherapy and 3/11 patients had prior radiotherapy. Median number of cryoprobes was 4, [IQR, 3–6 cryoprobes], thermoprotective measures to protect surrounding organs were required for 10/16 procedures. After cryoablation, local control rate was 45.4% at a mean follow-up of 11.7 months (range 3–34 months). Among the 16 cryoablation procedures, four resulted in complications, two were considered major complications: one septic shock on inhalation pneumopathy during extubation, requiring intensive care; and one dysphonia due to a recurrent nerve injury. Conclusion Cryoablation as a salvage treatment for recurrence of head and neck tumors after surgery and/or radiotherapy is an effective option, especially for patients that cannot benefit from salvage surgery.
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Methods and Materials This retrospective study reviewed 11 consecutive patients with head and neck cancer recurrence after primary treatment by surgery and radiotherapy, treated with cryoablation between 2016 and 2 020. Efficacy was measured by local control rate evaluated on MRI or/and PET. Tumor characteristics, number of cryoprobes, thermoprotective measures and complications were documented. Results Sixteen cryoablation procedures were performed in 11 patients with head and neck cancer recurrence after surgery or radiotherapy, deemed ineligible for classic salvage treatment. Among 11 patients, four were treated for an epidermoid carcinoma, four for an adenocarcinoma and three for other types: 1 muco-epidermoid carcinoma, 1 adenoid cystic carcinoma and 1 esthesioneuroblastoma, 10/11 patients had prior surgery, 7/11 patients had prior chemotherapy and 3/11 patients had prior radiotherapy. Median number of cryoprobes was 4, [IQR, 3–6 cryoprobes], thermoprotective measures to protect surrounding organs were required for 10/16 procedures. After cryoablation, local control rate was 45.4% at a mean follow-up of 11.7 months (range 3–34 months). Among the 16 cryoablation procedures, four resulted in complications, two were considered major complications: one septic shock on inhalation pneumopathy during extubation, requiring intensive care; and one dysphonia due to a recurrent nerve injury. Conclusion Cryoablation as a salvage treatment for recurrence of head and neck tumors after surgery and/or radiotherapy is an effective option, especially for patients that cannot benefit from salvage surgery.</description><identifier>ISSN: 0174-1551</identifier><identifier>EISSN: 1432-086X</identifier><identifier>DOI: 10.1007/s00270-022-03120-3</identifier><identifier>PMID: 35378612</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Adenocarcinoma ; Adenoid ; Cancer ; Carcinoma, Squamous Cell ; Cardiology ; Chemotherapy ; Clinical Investigation ; Complications ; Cryoprobes ; Cryosurgery - methods ; Head &amp; neck cancer ; Head and Neck Neoplasms - diagnostic imaging ; Head and Neck Neoplasms - surgery ; Humans ; Imaging ; Inhalation ; Life Sciences ; Magnetic resonance imaging ; Medicine ; Medicine &amp; Public Health ; Neoplasm Recurrence, Local - diagnostic imaging ; Neoplasm Recurrence, Local - surgery ; Neuroblastoma ; Non-Vascular Interventions ; Nuclear Medicine ; Olfactory epithelium ; Organs ; Patients ; Positron emission ; Radiation therapy ; Radiology ; Respiration ; Retrospective Studies ; Santé publique et épidémiologie ; Septic shock ; Surgery ; Tomography ; Treatment Outcome ; Tumors ; Ultrasound</subject><ispartof>Cardiovascular and interventional radiology, 2022-06, Vol.45 (6), p.791-799</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2022</rights><rights>2022. 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Methods and Materials This retrospective study reviewed 11 consecutive patients with head and neck cancer recurrence after primary treatment by surgery and radiotherapy, treated with cryoablation between 2016 and 2 020. Efficacy was measured by local control rate evaluated on MRI or/and PET. Tumor characteristics, number of cryoprobes, thermoprotective measures and complications were documented. Results Sixteen cryoablation procedures were performed in 11 patients with head and neck cancer recurrence after surgery or radiotherapy, deemed ineligible for classic salvage treatment. Among 11 patients, four were treated for an epidermoid carcinoma, four for an adenocarcinoma and three for other types: 1 muco-epidermoid carcinoma, 1 adenoid cystic carcinoma and 1 esthesioneuroblastoma, 10/11 patients had prior surgery, 7/11 patients had prior chemotherapy and 3/11 patients had prior radiotherapy. Median number of cryoprobes was 4, [IQR, 3–6 cryoprobes], thermoprotective measures to protect surrounding organs were required for 10/16 procedures. After cryoablation, local control rate was 45.4% at a mean follow-up of 11.7 months (range 3–34 months). Among the 16 cryoablation procedures, four resulted in complications, two were considered major complications: one septic shock on inhalation pneumopathy during extubation, requiring intensive care; and one dysphonia due to a recurrent nerve injury. 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Methods and Materials This retrospective study reviewed 11 consecutive patients with head and neck cancer recurrence after primary treatment by surgery and radiotherapy, treated with cryoablation between 2016 and 2 020. Efficacy was measured by local control rate evaluated on MRI or/and PET. Tumor characteristics, number of cryoprobes, thermoprotective measures and complications were documented. Results Sixteen cryoablation procedures were performed in 11 patients with head and neck cancer recurrence after surgery or radiotherapy, deemed ineligible for classic salvage treatment. Among 11 patients, four were treated for an epidermoid carcinoma, four for an adenocarcinoma and three for other types: 1 muco-epidermoid carcinoma, 1 adenoid cystic carcinoma and 1 esthesioneuroblastoma, 10/11 patients had prior surgery, 7/11 patients had prior chemotherapy and 3/11 patients had prior radiotherapy. Median number of cryoprobes was 4, [IQR, 3–6 cryoprobes], thermoprotective measures to protect surrounding organs were required for 10/16 procedures. After cryoablation, local control rate was 45.4% at a mean follow-up of 11.7 months (range 3–34 months). Among the 16 cryoablation procedures, four resulted in complications, two were considered major complications: one septic shock on inhalation pneumopathy during extubation, requiring intensive care; and one dysphonia due to a recurrent nerve injury. Conclusion Cryoablation as a salvage treatment for recurrence of head and neck tumors after surgery and/or radiotherapy is an effective option, especially for patients that cannot benefit from salvage surgery.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>35378612</pmid><doi>10.1007/s00270-022-03120-3</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-8637-4593</orcidid></addata></record>
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subjects Adenocarcinoma
Adenoid
Cancer
Carcinoma, Squamous Cell
Cardiology
Chemotherapy
Clinical Investigation
Complications
Cryoprobes
Cryosurgery - methods
Head & neck cancer
Head and Neck Neoplasms - diagnostic imaging
Head and Neck Neoplasms - surgery
Humans
Imaging
Inhalation
Life Sciences
Magnetic resonance imaging
Medicine
Medicine & Public Health
Neoplasm Recurrence, Local - diagnostic imaging
Neoplasm Recurrence, Local - surgery
Neuroblastoma
Non-Vascular Interventions
Nuclear Medicine
Olfactory epithelium
Organs
Patients
Positron emission
Radiation therapy
Radiology
Respiration
Retrospective Studies
Santé publique et épidémiologie
Septic shock
Surgery
Tomography
Treatment Outcome
Tumors
Ultrasound
title Percutaneous Cryoablation for Recurrent Head and Neck Tumors
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