Delayed increase of plasma selenoproteins and absence of side effect induced by infusion of pharmacological dose of sodium selenite in septic shock: Secondary analysis of a multicenter, randomized controlled trial

BACKGROUNDIn sepsis, neutrophil respiratory bursts participate in endothelium damage, the first step to multiple organ failure. In plasma two antioxidant selenoenzymes, which protect the endothelium, decrease: selenoprotein-P, and to a lesser extent glutathione peroxidase (GPX3). Sodium selenite (Na...

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Veröffentlicht in:Journal of trace elements in medicine and biology 2022-09, Vol.73, p.127031-127031, Article 127031
Hauptverfasser: Forceville, Xavier, Laviolle, Bruno, Gromadzinska, Jolanta, Boutten, Anne, Van Antwerpen, Pierre, Plouvier, Elisabeth, Annane, Djillali, Bellissant, Eric
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Sprache:eng
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