The GPR88 agonist RTI‐13951‐33 reduces alcohol drinking and seeking in mice

GPR88 is an orphan G‐protein‐coupled receptor that is considered a potential target to treat neuropsychiatric disorders, including addiction. Most knowledge about GPR88 function stems from knockout mouse studies, and in vivo pharmacology is still scarce. Here we examine the effects of the novel brai...

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Veröffentlicht in:	Addiction biology 2022-11, Vol.27 (6), p.e13227-n/a
Hauptverfasser:	Ben Hamida, Sami, Carter, Michelle, Darcq, Emmanuel, Sourty, Marion, Rahman, Md Toufiqur, Decker, Ann M., Jin, Chunyang, Kieffer, Brigitte L.
Format:	Artikel
Sprache:	eng
Schlagworte:	agonist Alcohol Drinking - psychology alcohol use disorder Alcoholism - drug therapy Animals Ethanol - pharmacology GPR88 Human health and pathology in vivo pharmacology Life Sciences Mice Mice, Inbred C57BL Mice, Knockout mouse behaviour Receptors, G-Protein-Coupled
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